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ProteomicsMyh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease
Impaired alveolar formation and maintenance are features of many pulmonary diseases that are associated with significant morbidity and mortality. In a forward genetic screen for modulators of mouse lung development, we identified the non-muscle myosin II heavy chain gene, Myh10. Myh10 mutant pups ex...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-19 | PXD011139 | Pride
Myh10/nm iib  ecm remodeling  mmp  thbs  lung development  emphysema 
TranscriptomicsmiRNA profile in colon cancer cell culture
The hypothesis that the onset and development of colorectal cancer result from the alteration of the close cooperation of mRNA-miRNA has gained increasing popularity. We performed a multifaceted enrichment analysis of hypernetworks, taking advantage of the simultaneous evaluation of transcriptome an...
ORGANISM(S): Homo sapiens 
2014-09-30 | E-MTAB-2704 | biostudies-arrayexpress
TranscriptomicsThe transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defense in skeletal muscles
Transcriptional microarray analysis was conducted on gastrocnemius muscle of control and PGC-1β(i)skm-/- mice one week after the last tamoxifen administration using the Affymetrix Mouse Gene 1.0 ST. each sample represent a pool of 3 different mice.
ORGANISM(S): Mus musculus 
2015-12-16 | E-GEOD-73572 | biostudies-arrayexpress
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