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TranscriptomicsWhole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum
Transcriptional analysis of L. infantum promastigote compared to L. infantum intracellular amastigote and transcriptional analysis of L. infantum promastigote compared to L. infantum axenic amastigote. The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.infantum...
ORGANISM(S): Leishmania infantum 
2010-05-14 | E-GEOD-13983 | biostudies-arrayexpress
ProteomicsA new role for the DEAD-box RNA helicase DDX3 in co-translational protein quality control
DEAD-box RNA helicases are central players in RNA metabolism, however, their role in translation regulation is largely unexplored in parasitic protozoa. Here, we have investigated the role of DDX3 RNA helicase in ribosome-associated protein quality control in Leishmania. We show that ribosomes move ...
ORGANISM(S): Leishmania infantum 
2021-07-23 | PXD020667 | Pride
Ribosome Leishmania infantum Ddx3 Label-free quantitative proteomics Cotranslational protein ubiquitination Orbitrap fusion 
UnknownSTAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).
Not available
S-EPMC3759668 | biostudies-literature
MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
TranscriptomicsTranscriptional analysis of wild-type Leishmania species between both stages using full-genome DNA microarrays
Transcriptional analyses of L. infantum promastigote compared to L. infantum intracellular amastigote, and L. major promastigote compared to L. major intracellular amastigote The full-genome DNA microarray includes one 70mer-oligonucleotide probe for each gene of L. infantum and for each gene of L....
ORGANISM(S): Leishmania major 
2008-05-28 | E-GEOD-10407 | biostudies-arrayexpress
UnknownGenetic testing of Behcet's disease using next-generation sequencing to identify monogenic mimics and HLA-B*51.
Not available
S-EPMC11636563 | biostudies-literature
UnknownAn open-label, phase IV randomised controlled trial of two schedules of a four-component meningococcal B vaccine in UK preterm infants.
Not available
S-EPMC11503106 | biostudies-literature
UnknownDual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation.
Not available
S-EPMC4934080 | biostudies-literature
ProteomicsFunctional characterization of the p97/valosin-containing protein (VCP) interacting network in Leishmania Functional characterization of the p97/valosin-containing protein (VCP) interacting network in Leishmania
Valosin‐containing protein (VCP)/p97/Cdc48 is an essential AAA+ ATPase associated with many ubiquitin-dependent cellular pathways that plays a central role in protein quality control in all eukaryotes. Its functional diversity relies on its ability to cooperate with a large number of protein cofacto...
ORGANISM(S): Leishmania infantum JPCM5 
2020-08-06 | PXD013731 | Pride
Leishmania  vcp/p97  vcp cofactors  co-immunoprecipitation  lc-ms/ms  network proteomics 
TranscriptomicsComparative Genomic Hybridization of Leishmania major methotrexate resistant strains vs wild-type LV39
CGH analysis of the drug resistant strain L. major MTX60.4 vs the wild-type strain LV39 The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.major LV39 Keywords: drug resistance Two-condition experiment, resistant strain MTX60.4 vs wild-type LV39. Three biologic...
ORGANISM(S): Leishmania major 
2008-05-31 | E-GEOD-11623 | biostudies-arrayexpress
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