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GenomicsA CRISPR knockout screen revealed modulators of Chlamydia trachomatis parasitophorous vacuole stability
Chlamydia trachomatis is a prevalent bacterial cause of urogenital and ocular infections. The pathogen uses the effector CpoS to suppress a host defense response that aborts intracellular bacterial growth by inducing host cell death. We conducted a CRISPR knockout screen to identify host genes contr...
ORGANISM(S): Homo sapiens 
2025-07-10 | E-MTAB-15337 | biostudies-arrayexpress
GenomicsA CRISPR knockout screen revealed modulators of Chlamydia trachomatis parasitophorous vacuole stability
A CRISPR knockout screen revealed modulators of Chlamydia trachomatis parasitophorous vacuole stability
PRJEB92212 | ENA
ProteomicsBioID reveals novel proteins of the Plasmodium parasitophorous vacuole membrane
During their development within the vertebrate host, Plasmodium parasites infect hepatocytes and red blood cells. Within these cells, parasites are surrounded by a parasitophorous vacuole membrane (PVM). The PVM plays an essential role for the interaction of parasites with their host cells, however ...
ORGANISM(S): Plasmodium berghei ANKA 
2018-01-03 | PXD007857 | Pride
Malaria Bioid Plasmodium berghei Plasma membrane 
GenomicsToxoplasma proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole.
Toxoplasma proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole.
PRJNA275621 | ENA
TranscriptomicsToxoplasma proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole.
Purpose: Two secreted Toxoplasma proteins (GRA17 and GRA23) mediate the passage of small molecules between the host cytoplasm and the parasite-containing vacuole. This provides the first molecular explanation to how intracellular, vacuole-residing parasites in the phylum Apicomplexa, like Plasmodium...
ORGANISM(S): Toxoplasma gondii RH Mus musculus 
2015-05-01 | GSE65980 | GEO
UnknownLeishmania amazonensis Engages CD36 to Drive Parasitophorous Vacuole Maturation.
Not available
S-EPMC4900624 | biostudies-literature
TranscriptomicsA Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma actively remodels the transcriptome of its hosting cells with profound and coupled impact on the host immune response. ...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-38782 | biostudies-arrayexpress
ProteomicsProximity-labeling reveals novel host and parasite proteins at the Toxoplasma parasitophorous vacuole membrane
Cygan AM, Jean Beltran PM, Branon TC, Ting AY, Carr SA, Boothroyd JC. 2021. Toxoplasma gondii is a ubiquitous, intracellular parasite that envelopes its parasitophorous vacuole with a protein-laden membrane (PVM). The PVM is critical for interactions with the infected host cell such as nutrient tran...
ORGANISM(S): Toxoplasma Gondii (ncbitaxon:5811) Homo Sapiens (ncbitaxon:9606) 
2021-02-10 | MSV000086833 | MassIVE
UnknownPlasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole.
Not available
S-EPMC2914058 | biostudies-literature
UnknownQuantitative Dextran Trafficking to the Coxiella burnetii Parasitophorous Vacuole.
Not available
S-EPMC5558434 | biostudies-literature
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