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MetabolomicsThe response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis

Drastic alteration in macronutrients causes large changes in gene expression in the photosynthetic unicellular alga Chlamydomonas reinhardtii. Preliminary data suggested that cells follow a biphasic response to this change hinging on the initiation of lipid accumulation, and we hypothesized that ...

2015-06-29 | MTBLS208 | MetaboLights
TranscriptomicsGene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1.
To get insight in the functional role of EGR2 for Ewing sarcoma, we performed a transcriptional profiling of Ewing sarcoma cells after knockdown of EGR2 and compared the resulting transcriptional signature with that of EWSR1-FLI1-silenced Ewing sarcoma cells. In accordance with the strong EGR2-induc...
ORGANISM(S): Homo sapiens 
2015-07-26 | E-GEOD-62090 | biostudies-arrayexpress
UnknownER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ.
Not available
S-EPMC7190750 | biostudies-literature
MetabolomicsAn ancient residue metabolomics-based method to distinguish use of closely related plant species in ancient pipes

Residues from ancient artifacts can help identify which plant species were used for their psychoactive properties, providing important information regarding the deep-time co-evolutionary relationship between plants and humans. However, relying on the presence or absence of one or several biomarke...

2020-07-21 | MTBLS890 | MetaboLights
TranscriptomicsHierarchical synergy of Pten, p53 and Rb pathways in high-grade astrocytoma induced in adult brain
Mutations in the PTEN, TP53 and RB1 pathways are obligate events in the pathogenesis of human glioblastomas, the highest grade of astrocytoma. To investigate synergy between these tumor suppressors in mice, we induced various combinations of compound deletions conditionally in astrocytes and neural ...
ORGANISM(S): Mus musculus 
2011-03-23 | E-GEOD-22927 | biostudies-arrayexpress
UnknownAssessing US Small Animal Veterinary Clinic Adaptations and Their Impacts on Workforce COVID-19 Preparedness and Response.
Not available
S-EPMC10777815 | biostudies-literature
UnknownWHO/IUIS Allergen Nomenclature: Providing a common language.
Not available
S-EPMC6019191 | biostudies-literature
ProteomicsMultiomics Analyses of Vesicular Transport Pathway-Specific Transcripts and Proteins in Ovine Amnion: Responses to Altered Intramembranous Transport
Amniotic fluid volume (AFV) is determined primarily by the rate of intramembranous (IM) transport of AF cross the amnion. Intramembranous transport is characterized as vesicular endocytotic and transcytotic processes regulated by fetal urine-derived stimulators and AF inhibitors. Our objectives were...
ORGANISM(S): Ovis aries 
2021-07-21 | PXD013135 | Pride
Amniotic fluid volume Intramembranous absorption Isobaric labeling Proteomics Vesicular transport Internal reference scaling Transcriptomics 
UnknownDynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing.
Not available
S-EPMC3488221 | biostudies-literature
UnknownLocalized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta.
Not available
S-EPMC8237619 | biostudies-literature
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