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Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
Obesity and insulin resistance are associated with oxidative stress, which may be implicated in their progression. The kinase JNK1 emerged as a promising drug target for the treatment of obesity and type-2 diabetes. However, JNK1 is a key mediator of the oxidative stress response, promoting either c...
ORGANISM(S): Mus musculus 
Glavey SV, Naba A, Manier S, Clauser KR, Tahri S, Park J, Reagan MR, Moschetta M, Mishima Y, Gambella M, Rocci A, Sacco A, Asara JM, Palumbo A, Roccaro AM, Hynes RO, Ghobrial IM. The extracellular matrix (ECM) is a major component of the tumor microenvironment, contributing to the regulation of cell...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-01-06 | MSV000080451 | MassIVE
Psoriasis and atopic dermatitis (AD) are characterized by polarized CD4+ T cell responses. During the polarization of naM-CM-/ve CD4+ T cells, DNA methylation plays an important role in the regulation of gene transcription. In this study, we profiled the genome-wide DNA methylation status of naM-CM-...
ORGANISM(S): Homo sapiens 
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