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ProteomicshDPSC secretome restores cognitive function and synaptic plasticity by reducing ROS and alleviating neuroinflammation through M2 microglial polarization after ischemic stroke
Ischemic stroke triggers a cascade of oxidative stress, neuroinflammation, and synaptic dysfunction, leading to long-term cognitive and motor deficits. The human dental pulp stem cell (hDPSC) secretome, derived from neural crest-origin cells, has emerged as a promising cell-free therapeutic candidat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-09-07 | PXD062727 | Pride
ProteomicsIntegrated Quantitative Phosphoproteomics and Cell-based Functional Screening Reveals Specific Pathological Cardiac Hypertrophy-related Phosphorylation Sites
Ventricle arrhythmias and atrial fibrillation resulting from alternation of intracellular Ca2+ handling capacity leads to pathological cardiac hypertrophy. Junctate-1 TG mouse model is considered as a genetic model of clinical relevant atrial fibrillation. Phosphorylation is one of the most importan...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD011421 | Pride
Cell-based screening Lc-ms/ms Cardiac hypertrophy Phosphoproteome 
ProteomicsPathological and physiological cardiac hypertrophy
This project is the comparison of protein profiles for pathological and physiological mouse cardiac hypertrophy
ORGANISM(S): Mus musculus (Mouse) 
2018-07-30 | PXD010165 | Pride
Cardiac hypertrophy Lc-ms/ms 
ProteomicsComparison of LC-MS/MS and real-time PCR assays for the efficient detection of potentially allergenic silkworm
The silkworm (Bombyx mori) has long been considered a source of food and medicine due to its high nutritional, medicinal, and economic value in East Asia. However, in some sensitive individuals, silkworm consumption can cause allergenic reactions such as vomiting, asthma, and anaphylaxis. Therefore,...
ORGANISM(S): Bombyx mori (Silk moth) 
2024-05-24 | PXD042494 | Pride
Real-time pcr Model cookies Alpha-amlyase Lipoprotein Bombyx mori Silkworm Lc-ms/ms 
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