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TranscriptomicsTranscription profiling of rat liver to examine aging induced alterations in hepatic gene expression
Toxicokinetic and metabolism studies are considered crucial to dose setting and interpretation of data from rodent carcinogenicity studies. The metabolism and distribution studies are usually conducted in 6 to 8 week old rodents. However cancer studies generally involve exposures from 6 weeks of a...
ORGANISM(S): Rattus norvegicus 
2008-06-18 | E-GEOD-4270 | biostudies-arrayexpress
UnknownCrystal structure of a putative methyltransferase from Mycobacterium tuberculosis: misannotation of a genome clarified by protein structural analysis.
Not available
S-EPMC164883 | biostudies-literature
TranscriptomicsTranscription profiling of rat liver throughout the day
One µg of total RNA from either an; individual rat or from a pooled sample was amplified and labeled with a; fluorescent dye (either Cy3 or Cy5) using the Low RNA Input Linear Amplification Labeling kit (Agilent Technologies, Palo Alto, CA) following the manufacturerâ??s protocol. The amount and qu...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-2441 | biostudies-arrayexpress
UnknownTowards unraveling the human tooth transcriptome: the dentome.
Not available
S-EPMC4388651 | biostudies-literature
UnknownIdentification of Distinct Arterial Waveform Clusters and a Longitudinal Evaluation of Their Clinical Usefulness.
Not available
S-EPMC6742504 | biostudies-literature
UnknownEffect of Monthly, High-Dose, Long-Term Vitamin D Supplementation on Central Blood Pressure Parameters: A Randomized Controlled Trial Substudy.
Not available
S-EPMC5721873 | biostudies-literature
UnknownNetwork-specific selectivity of functional connections in the neonatal brain.
Not available
S-EPMC9977389 | biostudies-literature
TranscriptomicsSilencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape mechanisms
Breast cancer metastasis to bone is a critical determinant of long-term survival after treatment of primary tumors. We used a mouse model of spontaneous bone metastasis to determine new molecular mechanisms. Differential transcriptome comparisons of primary and metastatic tumor cells revealed that a...
ORGANISM(S): Mus musculus 
2012-07-17 | E-GEOD-37828 | biostudies-arrayexpress
TranscriptomicsExtensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection [DGE-seq]
The human genome shares a remarkable amount of genomic sequence with our closest living primate relatives. Researchers have long sought to understand what regions of the genome are responsible for unique species-specific traits. Previous studies have shown that many genes are differentially expresse...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-54906 | biostudies-arrayexpress
GenomicsExtensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection [Dnase-seq]
The human genome shares a remarkable amount of genomic sequence with our closest living primate relatives. Researchers have long sought to understand what regions of the genome are responsible for unique species-specific traits. Previous studies have shown that many genes are differentially expresse...
ORGANISM(S): Macaca mulatta 
2014-02-13 | E-GEOD-54907 | biostudies-arrayexpress
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