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GenomicsNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes [ChIP-Seq]
Purpose: This study was carried out to determine the consequences of the Rfx2-/- genotype on spermatogenesis in the mouse Methods: DNA was extracted from decapsulated testes of 21 day old mice. ChIP sequencing was used to determine the binding sites of RFX2. Results: ChIP-Seq analysis identified ~88...
ORGANISM(S): Mus musculus 
2015-11-02 | E-GEOD-68282 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 30 [RNA-Seq P30]
Purpose: This study was carried out to determine the consequences of the Rfx2-/- genotype on spermatogenesis in the mouse Methods: RNA was extracted from decapsulated testes of 29-30 day old mixed background mice of either genotype. Deep sequencing was used to determine quantitative expression of th...
ORGANISM(S): Mus musculus 
2015-11-02 | E-GEOD-68283 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes at post natal day 21 [RNA-Seq P21]
Purpose: This study was carried out to determine the consequences of the Rfx2-/- genotype on spermatogenesis in the mouse Methods: RNA was extracted from decapsulated testes of 21 day old mixed background mice of either genotype. Deep sequencing was used to determine quantitative expression of the g...
ORGANISM(S): Mus musculus 
2015-11-02 | E-GEOD-68284 | biostudies-arrayexpress
GenomicsNext Generation Sequencing Analysis of Wild Type and Rfx2-/- Testicular Transcriptomes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-11-02 | E-GEOD-63130 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of murine embryos lacking endogenous retinoic acid signaling
Retinoic acid (RA), an active derivative of the liposoluble vitamin A (retinol), acts as an important signaling molecule during embryonic development, regulating phenomenons as diverse as anterior-posterior axial patterning, forebrain and optic vesicle development, specification of hindbrain rhombom...
ORGANISM(S): Mus musculus 
2013-03-31 | E-GEOD-43578 | biostudies-arrayexpress
TranscriptomicsMolar and incisor development
One of the key questions in developmental biology is how from universally shared molecular mechanisms and pathways, is it possible to generate organs displaying similar or complementary functions, with a wide range of different shapes or tissue organization? The dentition represents a valuable syste...
ORGANISM(S): Mus musculus 
2013-03-31 | E-GEOD-43144 | biostudies-arrayexpress
UnknownA targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.
Not available
S-EPMC4752661 | biostudies-literature
TranscriptomicsRSK2 is a modulator of craniofacial development
The RSK2 gene is responsible for Coffin-Lowry syndrome, an X-linked monogenic disease associating severe learning deficit andassociated to typical facial and digital abnormalities and skeletal changes. Craniofacial and dental anomalies encountered in this rare disease have been poorly characterized....
ORGANISM(S): Mus musculus 
2014-01-13 | E-GEOD-51034 | biostudies-arrayexpress
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