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TranscriptomicsEssential Roles of the Smc5/6 complex in Replication through Pausing Sites and Endogenous DNA Damage Tolerance
The essential functions of the conserved Smc5/6 complex remain elusive. To uncover its roles in genome maintenance, we established Saccharomyces cerevisiae cell cycle-regulated alleles that enable restriction of Smc5/6 components to S or G2/M. Unexpectedly, the essential functions of Smc5/6 segregat...
ORGANISM(S): Saccharomyces cerevisiae 
2015-11-19 | E-GEOD-72241 | biostudies-arrayexpress
UnknownAn observational feasibility study to assess the safety and effectiveness of intranasal fentanyl for radiofrequency ablations of the lumbar facet joints.
Not available
S-EPMC5315349 | biostudies-literature
TranscriptomicsKSRP-mediated Transcriptome reshaping
KSRP knock-down and BMP2 treatment produce a largely overlapping reshape of the transcriptome in C2C12 cells. microRNAs (miRNAs) are essential regulators of development, physiology, and evolution with miRNA biogenesis being strictly controlled at multiple levels. Regulatory proteins, such as KH-type...
ORGANISM(S): Mus musculus 
2013-06-25 | E-GEOD-38907 | biostudies-arrayexpress
UnknownEssential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.
Not available
S-EPMC4691243 | biostudies-literature
TranscriptomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors
In S. cerevisiae, replication timing is controlled by epigenetic mechanisms restricting the accessibility of origins to limiting initiation factors. About 30% of these origins are located within repetitive DNA sequences such as the ribosomal DNA (rDNA) array, but their regulation is poorly understoo...
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-03-26 | E-GEOD-56171 | biostudies-arrayexpress
UnknownHomologous recombination and Mus81 promote replication completion in response to replication fork blockage.
Not available
S-EPMC7332989 | biostudies-literature
GenomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae W303 
2014-05-14 | E-GEOD-57619 | biostudies-arrayexpress
GenomicsHDACs act on ribosomal DNA to control the yeast replication program and the competition between origins for limiting initiation factors [ChIP-seq]
In S. cerevisiae, replication timing is controlled by epigenetic mechanisms restricting the accessibility of origins to limiting initiation factors. About 30% of these origins are located within repetitive DNA sequences such as the ribosomal DNA (rDNA) array, but their regulation is poorly understoo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-14 | E-GEOD-57617 | biostudies-arrayexpress
UnknownA Novel Lipase from Streptomyces exfoliatus DSMZ 41693 for Biotechnological Applications.
Not available
S-EPMC10707221 | biostudies-literature
UnknownSARS-CoV-2-derived RNA replicons as safe and effective vaccines.
Not available
S-EPMC12501190 | biostudies-literature
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