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ProteomicsDisruption of STIM1-mediated Ca2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis and lean mass
STIM1 is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in store operated Ca2+ entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STIM1 is indispensable during development, its biological and metabolic functions in mature muscle ...
ORGANISM(S): Mus Musculus (mouse) 
2021-12-30 | PXD030674 | JPOST Repository
TranscriptomicsComparative proteomic and RNA-seq analyses identify glypican-3 as a hepatocyte host cell receptor for Plasmodium falciparum sporozoite invasion
Understanding the liver stage invasion and development of Plasmodium falciparum parasites is difficult due to limitations in current methodologies, namely, a hepatocyte cell line that supports the invasion of sporozoites. In this work we seek to develop and characterize a subclone of the HC-04 cell ...
ORGANISM(S): Homo sapiens 
2019-03-02 | E-MTAB-6919 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type cells vs Lmnb1 knockout cells
Comparison of gene expression profiles in wild type cells vs Lmnb1 knockout cells.
ORGANISM(S): Mus musculus 
2007-01-08 | E-MEXP-538 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type cells vs Rce1 knockout cells
Comparison of gene expression profiles of wild type cells vs Rce1 knockout cells.
ORGANISM(S): Mus musculus 
2007-01-08 | E-MEXP-539 | biostudies-arrayexpress
TranscriptomicsAxonal mRNA in human embryonic stem cell derived neurons
The identification of axonal mRNAs in model organisms has led to the discovery of many axonally translated proteins required for axon guidance and injury response. The extent to which these axonal mRNAs are conserved in humans is unknown. Here we report on the axonal transcriptome of glutamatergic n...
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-84975 | biostudies-arrayexpress
TranscriptomicsSCL006,icSARS CoV Urbani or icSARS Bat SRBD (spike receptor binding domain from the wild type strain Urbani to allow for infection of human and non-human primate cells) infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the cSARS Bat SRBD strain at MOI of 1.0. Cells samples were collected at 0, 7, 1...
ORGANISM(S): Homo sapiens 
2012-05-06 | E-GEOD-37827 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Icmt+/+ and Icmt-/- embryonic fibroblasts cells
Comparison of gene expression profiles of Icmt+/+ and Icmt-/- cells
ORGANISM(S): Mus musculus 
2007-01-08 | E-MEXP-540 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and dKO round spermatids Transcriptomes
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived WT and dKO round spermatids transcriptome profiling (RNA-seq) Methods: Adult WT and dKO round spermatids mRNA profiles mice were generated by d...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-59017 | biostudies-arrayexpress
GenomicOncoArray: Prostate Cancer

Original description of the study: From ELLIPSE (linked to the PRACTICAL consortium), we contributed ~78,000 SNPs to the OncoArray. A large fraction of the content was derived from the GWAS meta-analyses in European ancestry populations (overall and aggressive disease; ~27K SNPs). We also ...

phs001391 | dbGaP
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