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TranscriptomicsGenome-wide analysis of day 31 hESC-cardiomyocytes treated with DMSO (control) or retinoic acid (RA) during differentiation
Human embryonic stem cell-reporter line hESC-NKX2.5(eGFP/w) were differentiated to cardiomyocytes (CMs) by utilizing the spin embryoid body method. During differentiation the cells were treated with DMSO or retinoic acid (RA) from day 4-7. At day 31, cells were sorted based on GFP prior to RNA isola...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-61154 | biostudies-arrayexpress
TranscriptomicsA human fetal transcriptional atlas
Gene expression is highly dynamic during fetal development and determines tissue specification and function. In humans, the transcriptional profile of different organs during development has not been systematically studied. However, understanding how a particular tissue acquires its tissue identity ...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-66302 | biostudies-arrayexpress
MetabolomicsCross-modal Integration of Metabolomics and Cardiac Functionality Captures Dynamic Metabotoxic Effects of Doxorubicin in Engineered Heart Tissues

Functional stem cell-derived heart models offer new avenues for preclinical, animal-free physiological assessment of drug cardiotoxicity. Yet, comprehensive molecular profiling in these models remains limited, leaving key metabolic drivers of cardiotoxicity unexplored.

Here, we leveraged an...

2025-12-07 | MTBLS13225 | MetaboLights
UnknownDiscovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Not available
S-EPMC8172540 | biostudies-literature
UnknownFANTOM5 CAGE profiles of human and mouse samples.
Not available
S-EPMC5574368 | biostudies-literature
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