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TranscriptomicsAirway Epithelial Cell Response to Sendai virus infection
Oligonucleotide microarrays were used to establish a profile for gene expression in wild-type airway epithelial cells after paramyxoviral infection. Analysis was performed on mRNA isolated from SeV-infected primary-culture mouse tracheal epithelial cells that were maintained under physiologic condit...
ORGANISM(S): Mus musculus 
2009-04-25 | E-GEOD-10211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C57BL/6J strain infected with Sendai virus vs. UV irradiated virus to investigate virus-induced airway disease
Analysis of gene expression in lungs of C57BL/6J mice that develop chronic airway disease phenotypes after a single Sendai virus infection, compared with mice treated with UV-inactivated virus. Experiment Overall Design: Whole lung RNA was analyzed from 3 mice per condition per time point for days 2...
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-10964 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage response to sendai virus infection.
Thus, mouse macrophage cultures were established from PBMCs isolated from wild-type control mice and were inoculated with SeV (Sendai virus) or UV-SeV (UV-inactivated SeV). These microarrays were performed in concert with assays of CCL5 and CCR5 expression, viral replication, and cellular apoptosis....
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2935 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung from individuals with airway hyperactivity and goblet cell metaplasia post-Sendai virus infection
Mice representing phenotypic extremes of airway hyperreactivity and goblet cell metaplasia post-Sendai virus infection were identified from a 500 mouse F2 cohort (CB6F2/J). Whole lung RNA from 3 mice at each extreme was analyzed via microarray for gene expression. Subsequent pairwise comparisons b...
ORGANISM(S): Mus musculus 
2007-07-06 | E-GEOD-3925 | biostudies-arrayexpress
TranscriptomicsEffects of Myb shRNA on Airway Epithelial Cells
The epithelium of the pulmonary airway is specially differentiated to provide defense against environmental insults, but also subject to dysregulated differentiation that results in lung disease. The current paradigm for airway epithelial differentiation is a one-step program whereby a p63+ basal ep...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-60365 | biostudies-arrayexpress
TranscriptomicsGene Expression Effects of IL-13 on Primary Human Airway Epithelial Cells
Primary culture airway epithelial cells, grown under physiologic air-liquid interface conditions, with, or without IL-13 in order to study the effects of this cytokine on mucous cell metaplasia, an important feature of asthma and COPD. Keywords: IL13, mucus, goblet cell RNA was isolated from primary...
ORGANISM(S): Homo sapiens 
2012-12-04 | E-GEOD-37693 | biostudies-arrayexpress
TranscriptomicsVirus-Induced Airway Disease in Mice (C57BL/6J, d3)
Analysis of gene expression in lungs of C57BL/6J mice that develop chronic airway disease phenotypes after a single Sendai virus infection, compared with mice treated with UV-inactivated virus. Keywords: disease state analysis Whole lung RNA was analyzed from 3 mice per condition per time point 3 da...
ORGANISM(S): Mus musculus 
2015-03-27 | E-GEOD-61437 | biostudies-arrayexpress
TranscriptomicsVirus-Induced Airway Disease in Mice (C57BL/6J, d49)
Analysis of gene expression in lungs of C57BL/6J mice that develop chronic airway disease phenotypes after a single Sendai virus infection, compared with mice treated with UV-inactivated virus. Keywords: disease state analysis Whole lung RNA was analyzed from 3 mice per condition per time point 49 d...
ORGANISM(S): Mus musculus 
2013-08-08 | E-GEOD-49603 | biostudies-arrayexpress
UnknownExpert Strategies: Skull Base Reconstruction-Global Perspectives, Insights, and Algorithms through a Mixed Methods Approach.
Not available
S-EPMC12503090 | biostudies-literature
UnknownPolypill with or without Aspirin in Persons without Cardiovascular Disease.
Not available
S-EPMC7116860 | biostudies-literature
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