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MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
ProteomicsA Comprehensive Proteomics Study on Platelet Concentrates: Platelet Proteome, Storage Time and Mirasol Pathogen Reduction Technology
Platelet concentrates (PCs) represent a blood transfusion product with a major concern for safety as their storage temperature (20-24ºC) allows bacterial growth, and their maximum storage time period (less than a week) precludes complete microbiological testing. Pathogen inactivation technologies (P...
ORGANISM(S): Homo sapiens (Human) 
2018-03-23 | PXD008119 | Pride
Platelet function tests Storage time Platelet transfusion Pathogen inactivation technologies Blood safety Proteomics 
UnknownPathogen inactivation of red cell concentrates and whole blood: I. History, technologies and in vitro product preservation studies.
Not available
S-EPMC12926800 | biostudies-literature
UnknownInactivation of SARS-CoV-2 in All Blood Components Using Amotosalen/Ultraviolet A Light and Amustaline/Glutathione Pathogen Reduction Technologies.
Not available
S-EPMC9147860 | biostudies-literature
UnknownPlatelet Pathogen Reduction Technologies Alter the MicroRNA Profile of Platelet-Derived Microparticles.
Not available
S-EPMC7096552 | biostudies-literature
ProteomicsChemoproteomic profiling of host and pathogen enzymes active in cholera
Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active in animals infected with the cholera pathogen Vibrio cholerae. Four V. cholerae protease...
ORGANISM(S): Vibrio cholerae O1 str. VC91 
2016-02-22 | PXD003000 | Pride
Vibrio cholerae  rabbit 
ProteomicsInactivation of a NB-LRR plant immune-effector complex by post-translational modification
Modification of plant immune complexes by pathogen effectors can trigger strong immune responses mediated by the action of nucleotide binding-leucine rich repeat immune receptors. Although some strains of the pathogen Pseudomonas syringae harbor effectors that individually can trigger immunity, the ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Pseudomonas syringae 
2016-05-04 | PXD001344 | Pride
Mass spectrometry Arabidopsis thaliana Q-exactive Pseudomonas syringae Acetylation 
UnknownA Framework for Evaluation of New Processing Technologies in Human Milk Banking.
Not available
S-EPMC12508634 | biostudies-literature
UnknownEstablishment of an Inactivation Method for Ebola Virus and SARS-CoV-2 Suitable for Downstream Sequencing of Low Cell Numbers.
Not available
S-EPMC9958562 | biostudies-literature
UnknownHeat Inactivation of Nipah Virus for Downstream Single-Cell RNA Sequencing Does Not Interfere with Sample Quality.
Not available
S-EPMC10818917 | biostudies-literature
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