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GenomicsGenome-wide map of GATA6 DNA binding in human PDAC cells
By studying a mouse model, as well as human tumors samples and cell lines, we have revealed a tumor suppressive role for Gata6 in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). In order to understand the mechanism underlying such tumor suppressive function, we analyzed the genome-wide ...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-47535 | biostudies-arrayexpress
GenomicsGata6
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-47537 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression in the adult Gata6 null mouse pancreas
We report the global gene expression of mouse pancreatic cells in a pancreas-specific conditional knock-out mouse for Gata6, as compared with age-matched controls. Total RNA was extracted from the pancreas of 6-8 -week old mice of the two genotypes and analyzed. at this age, Gata6P-/- pancreata are ...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-47536 | biostudies-arrayexpress
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