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TranscriptomicsProx1 downregulation is a prerequisite for the maturation and expansion of postnatal murine beta cells
Alterations in the expression of key transcription factors can be harmful for pancreatic beta cell homeostasis and could lead to diabetes. This study uncovered that Prox1 overexpression obstructs beta cell maturation and results in severe hyperglycemia. The function of β-cells is key for glucose ho...
ORGANISM(S): Mus musculus 
2016-02-11 | E-GEOD-68133 | biostudies-arrayexpress
GenomicSTAMPEED: Northern Finland Birth Cohort 1966 (NFBC1966)

The Northern Finland Birth Cohorts program (NFBC) was initiated in the 1960s in the two northernmost provinces of Finland to study risk factors involved in pre-term birth and intrauterine growth retardation, and the consequences of these early adverse events on subsequent morbidity and mortality....

phs000276 | dbGaP
GenomicsUC
WTCCC2 project Ulcerative Colitis (UC) samples
EGAD00000000025 | EGA
GenomicsWTCCC2 case-control study for Ulcerative Colitis
WTCCC2 project genome-wide case-control association study for Ulcerative Colitis (UC) using the 1958 British Birth Cohort and the UK National Blood Service collections as controls.
EGAS00000000084 | EGA
GenomicsWTCCC2 project controls - 1958 British Birth Cohort and National Blood Service
WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service
EGAS00000000028 | EGA
GenomicsAS
WTCCC2 project samples from Ankylosing spondylitis Cohort
EGAD00010000150 | EGA
GenomicsGenomewide association studies in ankylosing spondylitis
The aim of this study was to identify genes associated with ankylosing spondylitis susceptibility in British and Australian individuals of European descent.
EGAS00000000104 | EGA
GenomicsExome chip analysis file
This data set includes the following summary level data file used for the exome chip analysis: exome_chip.sv.assoc.txt: results from single variant association analysis in exome chip
EGAD00010001187 | EGA
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
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