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TranscriptomicsTranscription profiling of yeast treated with rapamycin in a 7-part time series
This experiment was a 7-part time series (or, 2x7 factorial design) examining the effect of rapamycin on gene expression in Saccharomyces cerevisiae. Treated and untreated cultures were compared at 0, 20, 40, 60, 120, 240, and 360 minutes. In the paper, expression ratios (mRNA) at each time point ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-02-05 | E-TABM-639 | biostudies-arrayexpress
TranscriptomicsRNAseq of whole ovarian follicles from young and old mice.
Compare gene expression in whole ovarian follicles from young (6-12 weeks) and old (14-17 months) mice. Whole follicles,consist of the oocyte and granulosa cells. As oocytes are very difficult to extract intact from old follicles due to fibrosis, whole follicles were sequenced instead, so that old...
ORGANISM(S): Mus musculus 
2018-05-22 | E-MTAB-5952 | biostudies-arrayexpress
TranscriptomicsComprehensive Analysis of Hematopoietic Stem Cell Niche
HiSeq poly-A RNAseq of 13 murine bone marrow populations (C57BL/6NJ); 4 HSC, 7 Stromal, Macrophage, Megakaryocyte.
ORGANISM(S): Mus musculus 
2015-11-25 | E-MTAB-2923 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hematopoetic progenitor cells with Flk12+ Ncad-, Flk12- Ncad+, Flk12+ Ncad+ or Flk12- Ncad- phenotypes
N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells
ORGANISM(S): Mus musculus 
2008-01-04 | E-TABM-404 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast wild type and ggc1-delta strains after treatment with rapmycin
This experiment was a 4-part timeseries (or, 2x2x4 factorial design) designed to provide additional biological insight into the role of ggc1 in the rapamycin response of Saccharomyces cerevisiae. Treated and untreated cultures were compared at 0, 1, 2, and 4 hours of growth, in both WT and ggc1-del...
ORGANISM(S): Saccharomyces cerevisiae 
2010-01-07 | E-TABM-638 | biostudies-arrayexpress
Transcriptomicsenok_rnaseq
Investigation of role of Enok in Drosophila oocyte polarization by RNAseq
ORGANISM(S): Drosophila melanogaster 
2014-10-22 | E-MTAB-2521 | biostudies-arrayexpress
TranscriptomicsImprinting Affy
Murine long-term hematopoietic stem cells (HSCs), short-term HSCs and multipotent progenitor cells (MPPs) were isolated from bone marrow and expression profiled on Affy chips. The behavior of maternal-specific imprinting genes, particularly in the H19-Igf2 locus, was focused on, to see if any might...
ORGANISM(S): Mus musculus 
2013-08-12 | E-MTAB-1644 | biostudies-arrayexpress
TranscriptomicsImprinting RNAseq
Long-term hematopoietic stem cells (HSCs), short-term HSCs and multipotent progenitor cells (MPPs) were isolated from bone marrow of four mouse strains (WT, H19-deletion, Igf1r-deletion, and double-deletion) and expression profiled with RNAseq. The behavior of the transcriptomes, and in particular...
ORGANISM(S): Mus musculus 
2013-08-12 | E-MTAB-1628 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and myo1 knock out yeast to examine differential gene expression patterns in evolved mutants that can successfully perform cytokinesis
In general, yeast strains with myo1 knocked out cannot perform cytokinesis, but some evolve new ways of accomplishing the task. This is an examination of differential gene expression patterns in a selection of evolved mutants that can successfully perform cytokinesis. The purpose is to attempt a m...
ORGANISM(S): Saccharomyces cerevisiae 
2008-11-24 | E-TABM-559 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of yeast strains with different chromosome copy numbers
Aneuploidy, the condition of having an abnormal number of chromosomes, is a hallmark of cancer cells. Recent work performed in yeast and mouse models suggests that aneuploidy interferes with cell proliferation and organism development. However, other recent experiments suggested that aneuploidy migh...
ORGANISM(S): Saccharomyces cerevisiae 
2010-10-01 | E-MTAB-325 | biostudies-arrayexpress
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