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TranscriptomicsEpigenetic and immune function profiles associated with post-traumatic stress disorder
The biological underpinnings of post-traumatic stress disorder (PTSD) have not been fully elucidated. Previous work suggests that alterations in the immune system are characteristic of the disorder. Identifying the biological mechanisms by which such alterations occur could provide fundamental insig...
ORGANISM(S): Homo sapiens 
2010-05-12 | E-GEOD-21282 | biostudies-arrayexpress
TranscriptomicsAge associated differences in miRNA signatures are restricted to CD45RO negative T cells and are associated with changes in the cellular composition, activation and cellular ageing
MicroRNAs (miRNAs) have emerged as important players in the regulation of T-cell functionality. However, comprehensive insight into the extent of age-related miRNA changes in T cells is lacking. We established miRNA expression patterns of CD45RO- naïve and CD45RO+ memory T-cell subsets isolated from...
ORGANISM(S): Homo sapiens 
2015-05-23 | E-GEOD-69191 | biostudies-arrayexpress
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