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ProteomicsEffects of PGRMC1 phosphorylation status on MIA PaCa-2 cells
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014716 | Pride
Proteomics Swath Phosphorylation Pancreatic cancer 
ProteomicsCompare total proteomics profile of PaCa-2 cells using 1D and 2D IDA LC and SWATH analysis
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014789 | Pride
Cancer Proteomics Swath 
TranscriptomicsEffects of PGRMC1 phosphorylation on genome integrity and epigenetics
Progesterone receptor membrane component 1 (PGRMC1) is a protein that has been implicated in cancer biology and poor patient outcomes, which can be over-expressed in cancers, and exist in alternative states of phosphorylation.Here, we show that manipulation of PGRMC1 phosphorylation by mutagenesis r...
ORGANISM(S): Homo sapiens 
2019-12-01 | E-MTAB-8218 | biostudies-arrayexpress
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