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TranscriptomicsGeminin represses mesendoderm cell fate acquisition in embryoid bodies
Geminin is a small nucleoprotein that neuralizes ectoderm in the Xenopus embryo. Geminin promotes neural fate acquisition of mouse embryonic stem cells: Geminin knockdown during neural fate acquisition decreased expression of neural precursor cell markers (Pax6, Sox1), while increasing expression of...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-39676 | biostudies-arrayexpress
TranscriptomicsGene expression analysis after reconstitution of Ebf1-deficient pre-pro-B cells with Ebf1
Ebf1 deficient pre-pro B-cells (Fraction A) can be cultured in the presence of stromal feeders and cytokines. The retroviral transduction of these cells with Ebf1 was used as gain-of-function experiment for the analysis of direct and functional target genes of Ebf1. Ebf1 deficient pre-pro B-cells we...
ORGANISM(S): Mus musculus 
2010-07-29 | E-GEOD-21455 | biostudies-arrayexpress
TranscriptomicsQuantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and JNK inhibitors as a re-sensitising therapy
Glucocorticoids (GC) are pivotal in the treatment of childhood acute lymphoblastic leukaemia (ALL) but resistance is a continuing clinical problem with the underlying mechanisms still unclear. An isobaric tag proteomic approach was used to compare protein profiles of the B lineage ALL GC-sensitive c...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-63335 | biostudies-arrayexpress
ProteomicsPputida - Whole organism, NSAF (Lidburyetal,environmicrobiol,2016)
abundance based on NSAF, Interaction consistency score: 12.3, Coverage: 38
ORGANISM(S): 160488 
2016-00-00 | 1991256584 | PAXDB
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