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MetabolomicsInvestigating the Mechanisms of Silver Nanoparticle Toxicity in Daphnia magna: A Multi-Omics Approach
Silver nanoparticles (AgNPs), one of the most common nanomaterials in use today, have been shown to enter the aquatic environment from use of commercially obtained products. Although acute toxicity has been shown in vitro and in vivo, there is still a great deal of uncertainty surrounding the molecu...
2017-05-08 | MTBLS260 | MetaboLights
Transcriptomicsfumonisin biosynthesis
In the study, expression profiles in wild type and a fcc1 mutant were compared to identify genes with patterns of expression similar to the FUM genes. DNA microarrays were constructed with ESTs from cDNA libraries obtained from the fcc1 mutant and wild-type strain of F. verticillioides grown on maiz...
ORGANISM(S): Gibberella moniliformis 
2010-06-09 | E-GEOD-938 | biostudies-arrayexpress
MetabolomicsDirect infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control
Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computatio...
2022-05-16 | MTBLS79 | MetaboLights
UnknownComparative (computational) analysis of the DNA methylation status of trinucleotide repeat expansion diseases.
Not available
S-EPMC3884633 | biostudies-literature
UnknownComputational modeling investigation of pulsed high peak power microwaves and the potential for traumatic brain injury.
Not available
S-EPMC8555891 | biostudies-literature
MetabolomicsMetabolomics reveals an involvement of pantothenate for male production responding to the short-day stimulus in the water flea, Daphnia pulex
Under favorable conditions, the micro-crustacean Daphnia pulex produces female offspring by parthenogenesis, whereas in response to various unfavorable external cues, they produce male offspring to induce sexual reproduction (environmental sex determination: ESD). We recently established a suitable ...
2017-04-03 | MTBLS259 | MetaboLights
TranscriptomicsEfficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia
Alterations of IKZF1, encoding the lymphoid transcription factor IKAROS, are a hallmark of high risk acute lymphoblastic leukemia (ALL), however the role of IKZF1 alterations in ALL pathogenesis is poorly understood. Here we show that in mouse models of BCR-ABL1 leukemia, Ikzf1 and Arf alterations s...
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-68391 | biostudies-arrayexpress
UnknownAbstracts of the 33rd International Austrian Winter Symposium : Zell am See, Austria. 24-27 January 2018.
Not available
S-EPMC5780335 | biostudies-literature
MetabolomicsMapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variat...
2020-12-02 | MTBLS1188 | MetaboLights
UnknownIntensive vs Standard Blood Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial.
Not available
S-EPMC7056569 | biostudies-literature
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