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GenomicsGenome-wide maps of PBX3-binding site
We report the high-throughput profiling of PBX3-binding sites under liver cancer stem cell reprogramming driven by PBX3 overexpression. By obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide PBX3-binding maps of SMMC-7721 cells. This study pr...
ORGANISM(S): Homo sapiens 
2015-09-24 | GSE71260 | GEO
UnknownPBX3 is an important cofactor of HOXA9 in leukemogenesis.
Not available
S-EPMC3578957 | biostudies-literature
TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
UnknownPHAX enhanced LIN28B-mediated PBX3 mRNA stability to promote esophageal cancer development.
Not available
S-EPMC11875786 | biostudies-literature
UnknownPbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia.
Not available
S-EPMC4486225 | biostudies-literature
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
UnknownPBX3 as a biomarker for the early diagnosis and prediction of prognosis of glioma.
Not available
S-EPMC10849273 | biostudies-literature
UnknownRegulation of PBX3 expression by androgen and Let-7d in prostate cancer.
Not available
S-EPMC3112428 | biostudies-literature
UnknownPBX3 promotes pentose phosphate pathway and colorectal cancer progression by enhancing G6PD expression.
Not available
S-EPMC10535713 | biostudies-literature
UnknownThe transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the tumor suppressor p53.
Not available
S-EPMC8564524 | biostudies-literature
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