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TranscriptomicsTranscription profiling of human H69 xenograft tumors in mice following PDT treatment.
The response of tumors to PDT treatment is expected to provide information on effects of oxygen depletion, induced apoptosis, induction of an inflammatory response and induction of an ani-tumor immune response. Experiment Overall Design: NCI-H69 human SCLC xenografts were induced in SCID mice. Thre...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8920 | biostudies-arrayexpress
TranscriptomicsLow-power photodynamic therapy induces survival signaling in cultured hilar cholangiocarcinoma cells
Photodynamic therapy (PDT) of solid cancers comprises the administration of a photosensitizer followed by illumination of the photosensitizerreplete tumor with laser light. This induces a state of local oxidative stress, culminating in the destruction of tumor tissue and microvasculature and inducti...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-68292 | biostudies-arrayexpress
TranscriptomicsHuman SCC-13 Cells: Control vs. Resitant populations to photodynamic therapy (PDT)
aCGH of control cells not subjected to PDT (Parental) and cells subjected to 5 or 10 sequential PDT treatments (5M-BM-:G and 10M-BM-:G, respectively). Three-condition experiment, cultures of SCC-13 cells not subjected to PDT (Parental) vs 5M-BM-:G and 10M-BM-:G generations of resistant cells.
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-50602 | biostudies-arrayexpress
ProteomicsStudy of reversible oxidation of thiol proteins after hexyl aminolevulinate mediated photodynamic therapy
This proteomic study This proteomic study focuses on the role of reversible thiol oxidation after hexyl aminolevulinate mediated PDT (HAL-PDT). The human epidermoid carcinoma cell line A431 was used as model system and red light as light source, a clinical relevant in vitro model. The light dose dep...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080866 | MassIVE
TranscriptomicsLow dose PDT - Murine Cells
Murine prostate carcinoma cell lines TRAMP-C1 and TRAMP-C2 were grown for 16 h at 37M-0C with photosensitizer 5-aminolaevulinic acid (5-ALA; 50 M-5g/ml). Then, the cells were sublethally irradiated with laser light (635 nm) at room temperature (using RPMI1640 without phenol red as medium). After ph...
ORGANISM(S): Mus musculus 
2011-06-25 | E-MEXP-3016 | biostudies-arrayexpress
TranscriptomicsLow Dose PDT - Human Cells
Human tumour cell lines PC3, DU145, U87 and U373 (prostate carcinoma and glioblastoma) were treated with photosensitizers 5-aminolaevulinic acid (5-ALA) or photofrin. Then, the cells were irradiated sublethally with 635 nm laser light.
After photodynamic therapy, the cells were grown at 37°C for ...
ORGANISM(S): Homo sapiens 
2011-06-26 | E-MEXP-3020 | biostudies-arrayexpress
TranscriptomicsLow Dose PDT - Murine Tumors
Tumors were induced in C57BL/6 mice by subcutaneous injection of murine prostate carcinoma cell line TRAMP-C2. Tumor-bearing mice were narcotized, injected with photosensitizer 5-aminolaevulinic acid (5-ALA), shaven at their back, and 3-4 h later the whole tumor area was irradiated perpendicular (un...
ORGANISM(S): Mus musculus 
2011-06-25 | E-MEXP-3017 | biostudies-arrayexpress
UnknownTSPO 18 kDa (PBR) Targeted Photosensitizers for Cancer Imaging (PET) and PDT.
Not available
S-EPMC4018113 | biostudies-literature
ProteomicsChemoproteomics analysis revealed photodynamic therapy (PDT) effect of Novel Photo-switchable Photosensitizer
The study titled "Dyad system of BOAHY-BODIPY Conjugates as Novel Photo-switchable Photosensitizer for Photodynamic Therapy" investigated the photodynamic therapy (PDT) potential of a compound that switches structures (Z form to E form) under UV irradiation. The compound generates reactive oxygen sp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-13 | MSV000096072 | MassIVE
GenomicsResitant populations to photodynamic therapy (PDT) of squamous cell carcinoma cells (SCC-13)
Resitant populations to photodynamic therapy (PDT) of squamous cell carcinoma cells (SCC-13)
PRJNA747827 | ENA
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