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MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownGermline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.
Not available
S-EPMC2865728 | biostudies-literature
TranscriptomicsAnalysis of mouse T cell transcription profile after co-culture with BaF3 cells with or without the oncogenic point mutation JAK2 V617F
The activation of PD-1 (Programmed Death receptor-1) on T cells can cause T cell exhaustion and immune tolerance. Some tumors up-regulate the expression of the ligand of PD-1, namely PD-L1 (Programmed Death Receptor-Ligand 1), thus preventing anti-tumor immune response and promoting immune-escape. P...
ORGANISM(S): Mus musculus 
2018-12-01 | E-MTAB-5028 | biostudies-arrayexpress
MetabolomicsA Metabonomic Comparison of Human Serum and Plasma Subtypes Using Untargeted NMR Spectroscopy and UPLC-MS (NMR assays)
INTRODUCTION: Differences in the metabolite profiles between serum and plasma are incompletely understood. OBJECTIVES: To evaluate metabolic profile differences between serum and plasma and among plasma sample subtypes. METHODS: We analyzed serum, platelet rich plasma (PRP), platelet poo...
2018-07-25 | MTBLS470 | MetaboLights
UnknownVariation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer.
Not available
S-EPMC4082406 | biostudies-literature
UnknownLarge-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome.
Not available
S-EPMC4000890 | biostudies-literature
UnknownRisk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10.
Not available
S-EPMC3946482 | biostudies-literature
UnknownGWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Not available
S-EPMC3693183 | biostudies-literature
UnknownIdentification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Not available
S-EPMC3709460 | biostudies-literature
UnknownWhole-genome sequencing of patients with rare diseases in a national health system.
Not available
S-EPMC7610553 | biostudies-literature
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