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TranscriptomicsHuman skeletal muscle biopsies from a 3h IL-6 infusion
Skeletal muscle has been identified as a secretory organ. We hypothesized that IL-6, a cytokine secreted from skeletal muscle during exercise, could induce production of other secreted factors in skeletal muscle. Keywords: Human skeletal muscle time course response to IL-6 infusion IL-6 was infused...
ORGANISM(S): Homo sapiens 
2008-05-27 | E-GEOD-10685 | biostudies-arrayexpress
GenomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis (MeDIP-seq)
DNA methylation is tightly regulated throughout mammalian development and altered methylation patterns are a hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in acute myeloid leukemia (AML) and has been suggested to protect CpG islands and promoters from aberrant methyla...
ORGANISM(S): Mus musculus 
2015-04-22 | E-GEOD-59579 | biostudies-arrayexpress
TranscriptomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis [Agilent]
DNA methylation is tightly regulated throughout mammalian development and altered DNA methylation patterns are a general hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in hematological disorders, including acute myeloid leukemia (AML), and has been suggested to protect...
ORGANISM(S): Mus musculus 
2015-04-30 | E-GEOD-68415 | biostudies-arrayexpress
GenomicsThe colon KRAS/BRAF variants detection set - samples
Description not provided
EGAD00001000835 | EGA
GenomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis (eRRBS)
DNA methylation is tightly regulated throughout mammalian development and altered methylation patterns are a hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in acute myeloid leukemia (AML) and has been suggested to protect CpG islands and promoters from aberrant methyla...
ORGANISM(S): Mus musculus 
2015-04-22 | E-GEOD-59584 | biostudies-arrayexpress
TranscriptomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis (Affymetrix)
DNA methylation is tightly regulated throughout mammalian development and altered methylation patterns are a hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in acute myeloid leukemia (AML) and has been suggested to protect CpG islands and promoters from aberrant methyla...
ORGANISM(S): Mus musculus 
2015-04-22 | E-GEOD-59586 | biostudies-arrayexpress
GenomicsLoss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis (ChIP-seq)
DNA methylation is tightly regulated throughout mammalian development and altered methylation patterns are a hallmark of cancer. The methylcytosine dioxygenase TET2 is frequently mutated in acute myeloid leukemia (AML) and has been suggested to protect CpG islands and promoters from aberrant methyla...
ORGANISM(S): Mus musculus 
2015-04-22 | E-GEOD-59580 | biostudies-arrayexpress
GenomicsThe paired FF/FFPE colon set, RNA-Seq - samples
Description not provided
EGAD00001000831 | EGA
GenomicsThe paired FF/FFPE colon set, Exome-Seq - samples
Description not provided
EGAD00001000834 | EGA
GenomicsThe FF bladder signature conservation set - samples
Description not provided
EGAD00001000833 | EGA
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