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TranscriptomicsAffymetrix U133A array data for 111 pediatric acute myeloid leukemia (AML) samples at diagnosis
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML This study characterizes CNA and LOH, gene expression and gene sequence mutations in a representative cross-section through subtypes of pediatric AML. Keywords...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-14471 | biostudies-arrayexpress
TranscriptomicsGene expression profiles associated with pediatric relapsed AML
In high income countries 90% of the patients achieve complete remission after induction chemotherapy. However, 30-40% of these patients suffer from relapse. These patients face a dismal prognosis, as the majority (>60%) of relapsed patients die within 5 years. As a result, outcome for pediatric acut...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-52891 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pediatric acute myeloid leukemia samples
This series represents leukemic samples obtained from pediatric AML patients at diagnosis and control normal bone marrow samples.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2191 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Sty2 SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15731 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Hind SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15714 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Nsp SNP Array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-04-13 | E-GEOD-15730 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling in pediatric AML
MicroRNAs (miRNAs) play a pivotal role in the regulation of hematopoiesis and development of leukemia. Great interest emerged in modulating miRNA expression for therapeutic purposes. In order to identify miRNAs, which specifically suppress leukemic growth of AML with t(8;21), inv(16) or MLL-rearrang...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-52541 | biostudies-arrayexpress
TranscriptomicsmicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways
microRNAs, important regulators of cell proliferation and apoptosis, have been shown to be involved in the pathogenesis of acute myeloid leukemia in adulthood AML. However, comprehensive studies in AML of children and adolescents are missing so far. We investigated the miRNA expression profiles of d...
ORGANISM(S): Homo sapiens 
2013-09-11 | E-GEOD-35320 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for pediatric acute myeloid leukemia (AML) samples at diagnosis: Xba SNP array
Genome-wide profiling of Copy Number Alterations (CNA) and Loss of Heterozygosity (LOH), gene expression and resequencing of pediatric AML. This study characterizes the CNA and LOH in a representative cross-section through subtypes of pediatric AML. Affymetrix SNP arrays were performed according to ...
ORGANISM(S): Homo sapiens 
2010-01-03 | E-GEOD-15732 | biostudies-arrayexpress
TranscriptomicsGene expression profile of pediatric AML
Gene expression data were obtained from 130 pediatric AML patients who were enrolled on the AML99 study conducted by the Japanese Childhood AML Cooperative Study Group. RNA samples obtained at the time of diagnosis were analyzed using GeneChip Human Genome U133 plus 2.0 array (Affymetrix).
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-35784 | biostudies-arrayexpress
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