Peg-20 - OmicsDI

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Unknown (615)
Transcriptomics (189)
Genomics (69)
Proteomics (67)
Metabolomics (25)
Clinical (2)
Genomic (1)
Methylation profiling (1)

Organisms

Homo sapiens (86)
Mus musculus (77)
Arabidopsis thaliana (13)
Saccharomyces cerevisiae (6)
Rattus norvegicus (4)
Caenorhabditis elegans (3)
Gallus gallus (3)
Sus scrofa (3)
Drosophila melanogaster (3)
Neurospora discreta (2)
Sorghum bicolor (2)
Medicago truncatula (2)
Apis mellifera (2)
Mytilus californianus (2)
Influenza A virus (A/WSN/1933(H1N1)) (1)
Serendipita vermifera (1)
Neurospora tetrasperma (1)
dust metagenome (1)
human nasopharyngeal metagenome (1)
Xerophyta humilis (1)
Populus x canadensis (1)
Synechococcus phage S-IO17 (1)
Bartonella grahamii (1)
Arundo donax (1)
Cannabis sativa (1)
Gossypium hirsutum (1)
Brassica juncea (1)
Callithrix jacchus (1)
Leishmania major (1)
Rhizobium leguminosarum (1)

Organisms

Mus musculus (6)
Saccharomyces cerevisiae (5)
Homo sapiens (5)
Oryza sativa Japonica Group (2)
Saccharum hybrid cultivar ROC22 (1)
Vigna stipulacea (1)
Vigna aconitifolia (1)
Sesamum indicum (1)
Pseudomonas putida (1)
Populus trichocarpa (1)
Brassica napus (1)
Callithrix jacchus (1)
Manihot esculenta (1)
Fagopyrum tataricum (1)
Triticum aestivum (1)
Sorghum bicolor (1)
Oryza sativa (1)
Zea mays (1)
Arabidopsis thaliana (1)

Repository

biostudies-arrayexpress (201)
pride (60)
ENA (54)
MetabolomicsWorkbench (13)
MetaboLights (12)
geo (9)
iProX (3)
dbGaP (1)
jPOST (1)
MassIVE (1)

Tissue

Leaf (9)
Plant cell (7)
Cell culture (5)
Epithelial cell (5)
Blood (4)
Hepatocyte (3)
Root (3)
Whole body (3)
Blood plasma (2)
Brain (2)
Colon (2)
Liver (2)
Thyroid gland (2)
Bacterial cells (1)
Bone (1)
Brain (1)
Cultured cells (1)
Eye tissue (1)
Leukemia cells (1)
Plaque samples (1)
Roots (1)
Whole Tissue (1)
Artery (1)
B cell (1)
B-lymphocyte (1)
Blood (1)
Blood platelet (1)
Callus culture (1)
Cell suspension culture (1)
Chronic lymphocytic leukemia cell (1)

Disease

Disease free (3)
Porphyria NOS (2)
Normal (2)
Chronic lymphocytic leukemia (2)
Liver cancer (2)
Colon cancer Dukes C (1)
Infected with Influenza A/WSN/33 (H1N1) (1)
IV (1)
Primary tumor (1)
Bladder tumour (1)
Sarcoma (1)
Reference (1)
Prostate carcinoma (1)
Neuroblastoma (1)
Carcinoma, Hepatocellular (1)
Colorectal neoplasia (1)
COVID-19 (1)
Cancer (1)
Diabetes (1)
Drug addiction (1)
Eye disease (1)
Stress (1)
Trauma (1)
Cardiovascular system disease (1)
Colon cancer (1)
Pancreatic ductal carcinoma (1)
Skin cancer (1)
Thyroid cancer (1)
Tuberculosis (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (73)
Shotgun proteomics (34)
ESI (13)
Bottom-up proteomics (11)
Data-dependent acquisition (11)
Mass spectrometry (8)
Gel-based experiment (4)
Top-down proteomics (4)
Mass spectrometry assay (3)
NMR spectroscopy (2)
Data-independent acquisition (2)
SWATH MS (2)
Affinity purification coupled with mass spectrometry proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)

Instrument Platform

NextSeq 550 (9)
Illumina NovaSeq 6000 (6)
Illumina HiSeq 2000 (6)
NextSeq 500 (5)
Liquid Chromatography MS - negative - reverse phase (5)
Liquid Chromatography MS - positive - reverse phase (4)
DNBSEQ-G400 (3)
Sony SH800 (2)
ScanArray Express HT [PerkinElmer] (2)
Illumina HiSeq 2500 (2)
Gas Chromatography MS - positive (2)
Eppendorf EpMotion 5073m pipetting robot (1)
Microarray scanner system (1)
Agilent Scanner (1)
ArrayWoRx Biochip Reader [Applied Precision] (1)
Scanning hardware (1)
Sony SH800S (1)
Illumina HiSeq X (1)
GenePix 4000B (1)
BGISEQ-500 (1)
Illumina MiSeq (1)
Illumina HiSeq 4000 (1)
6546 Agilent Q-TOF (1)
Bruker (1)
Capillary electrophoresis MS - (1)
Diode array detection MS - alternating - reverse phase (1)
Liquid Chromatography MS - positive (1)
Nuclear Magnetic Resonance (NMR) - (1)
Orbitrap Elite (Thermo Scientific) (1)

Publication Date

2013 (34)
2014 (28)
2010 (25)
2015 (21)
2021 (18)
2025 (16)
2024 (16)
2016 (14)
2023 (13)
2009 (13)
2017 (12)
2022 (11)
2011 (11)
2026 (9)
2008 (8)
2020 (8)
2019 (7)
2018 (6)
2012 (6)
2007 (5)
2006 (3)
2005 (2)
2004 (1)

CHEBI ID

CHEBI:15366 (3)
CHEBI:16449 (3)
CHEBI:18186 (3)
CHEBI:136085 (2)
CHEBI:15428 (2)
CHEBI:16359 (2)
CHEBI:17351 (2)
CHEBI:17418 (2)
CHEBI:18237 (2)
CHEBI:24898 (2)
CHEBI:25017 (2)
CHEBI:25094 (2)
CHEBI:27266 (2)
CHEBI:28484 (2)
CHEBI:30768 (2)
CHEBI:30772 (2)
CHEBI:30776 (2)
CHEBI:30805 (2)
CHEBI:72998 (2)
CHEBI:78320 (2)
CHEBI:1148 (1)
CHEBI:131654 (1)
CHEBI:131655 (1)
CHEBI:131658 (1)
CHEBI:131659 (1)
CHEBI:131660 (1)
CHEBI:131661 (1)
CHEBI:131662 (1)
CHEBI:131663 (1)
CHEBI:131665 (1)

Metabolite Name

Linoleic acid (2)
PC(16:0/0:0) (2)
PC(18:2/18:2) (2)
1-palmitoyl-2-(9,10-epoxystearoyl)phosphatidylcholine (1)
2-Hydroxymyristic acid (1)
2-hydroxy-butyrate (1)
2-methyl-butyrate (1)
20-Hydroxyeicosatetraenoic acid (1)
25-Hydroxyvitamin-D3 (1)
2a-(Hydroxymethyl)-5a-androstane-3b,17b-diol (1)
3-Dehydroteasterone (1)
3alpha-hydroxy-5alpha-androstan-17-one 3-sulfate (1)
5,8,11-Eicosatriynoic acid (1)
8,11,14-Eicosatrien-5-ynoic acid (1)
9(cis)-retinal (Vitamin A) (1)
Acetate (1)
Acetylcarnitine (1)
Adenine (1)
Adenosine (1)
Arachidonic acid (1)
Butyrate (1)
Butyro-betaine (1)
Caproic acid (1)
Carnitine (1)
Cholic acid (1)
FA 12:0 (1)
FA 14:0 (1)
FA 16:0 (1)
FA 18:0 (1)
FA 18:1 (1)

First Public Date

2026 (10)
2025 (10)
2022 (6)
2024 (5)
2023 (4)
2021 (4)
2019 (4)
2017 (3)
2014 (3)
2020 (2)
2018 (1)
2015 (1)
2013 (1)

Study status

Active, not recruiting (1)
Terminated (1)

Study type

Transcription profiling by array (107)
RNA-seq of coding RNA (34)
ChIP-seq (14)
Other (8)
RNA-seq of coding RNA from single cells (8)
RNA-seq of non coding RNA (5)
Methylation profiling by array (4)
CLIP-seq (2)
Comparative genomic hybridization by array (2)
Interventional (2)
GRO-seq (1)
ChIP-chip by tiling array (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
Antigen profiling (1)
ATAC-seq (1)
Hi-C (1)
RIP-seq (1)
DNA-seq (1)
Proteomic profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2022 (84)
2025 (67)
2021 (61)
2023 (60)
2024 (57)
2014 (56)
2013 (52)
2015 (51)
2018 (45)
2019 (40)
2020 (40)
2016 (36)
2010 (33)
2017 (31)
2012 (22)
2011 (22)
2009 (18)
2026 (11)
2007 (11)
2008 (10)
2006 (4)
2005 (2)
2004 (2)
2003 (1)

Lab affiliation

Department of Genetics, Stanford University (2)
School of Biomedical Sciences and Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China (2)
Ascano Lab, Biochemistry Department, Vanderbilt University, Nashville TN, USA (1)
Assistant Professor at the School of Biomedical Sciences and Department of Pathology, The University of Hong Kong, Hong Kong (1)
Assistant Professor, Mass spectrometry Facility, Canadian Centre for Health and Safety in Agriculture, College of Medine, University of Saskatchewan. (1)
Assistant Profssor, School of Biomedical Sciences and Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China (1)
Associate Research Fellow, Institute of Plant and Microbial Biology Academia Sinica, Taipei, Taiwan (1)
BK21 Plus KNU Multi-Omics-based Creative Drug Research Team, College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Republic of Korea (1)
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, 37077 Goettingen, Germany (1)
CINVESTAV Department of Biochemistry (1)
Cancer Sciences, Faculty of Medicine, University of Southampton, UK (1)
Caris Science Inc (1)
Charles University, Faculty of Pharmacy in Hradec Králové,Department of Analytical Chemistry, Akademika Heyrovského 1203/8 500 05 Hradec Králové, Czech Republic (1)
Children’s Hospital of Philadelphia 3615 Civic Center Blvd. Philadelphia, PA 19104 (1)
Collaborative Innovation Center of Henan Grain Crops and State Key Laboratory of Wheat and Maize Crop Science/College of Agronomy, Henan Agricultural University, Zhengzhou, China 450001 (1)
College of Life Science, Capital Normal University, 100048 Beijing, China. (1)
College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China (1)
Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University (1)
Department of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203/8, 500 03 Hradec Králové, Czech Republic (1)
Department of Chemistry University of Virginia (1)
Department of Chemistry, Columbia University, New York, NY 10027 (1)
Department of Crop Genetics and Breeding, College of Agronomy, Gansu Agricultural University, Lanzhou, China. (1)
Departments of Chemistry, Biological Sciences, Microbiology and Immunology, Vanderbilt University (1)
Dept. Medical Biochemistry and Biophysics, Div. Chemistry I, Karolinska Institutet, Stockholm, Sweden (1)
Faculty of Natural Sciences, Keele University, UK (1)
Henan Agricultural University (1)
Institute for Biochemistry and Molecular Biology, University of Bonn, 53115 Bonn, Germany (1)
Institute for Genomics, Biocomputing, and Biotechnology, Mississippi State University, Mississippi State, MS 39759, USA (1)
KU Leuven – University of Leuven, Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, Herestraat 49 box 901b, 3000 Leuven, Belgium (1)
Lab head of System Oncology lab at CRUK Manchester Institute (1)

Location

Brazil (1)
China (1)
France (1)
Germany (1)
Italy (1)
South Korea (1)
Taiwan (1)
United Kingdom (1)
United States (1)

Keyword

ADI-PEG 20 (1)
Arginine (1)
Arginine deiminase (1)
Argininosuccinate synthetase (1)

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Effect of ADI-PEG 20 treatment on murine liver chromatin landscape at single cell resolution.

PRJNA791376 | ENA

Effect of ADI-PEG 20 treatment on murine liver chromatin landscape at single cell resolution.

We demonstrate the effects of 4-week ADI-PEG 20 on murine liver chromatin accessibility by single-cell ATAC-sequencing

ORGANISM(S): Mus musculus

2022-01-18 | GSE192413 | GEO

20 Korean Peg-Lateralis Cohort

PRJNA1013609 | ENA

Phase 1b study of pegylated arginine deiminase (ADI-PEG 20) plus Pembrolizumab in advanced solid cancers.

Not available

S-EPMC8276661 | biostudies-literature

Phase 1 trial of ADI-PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors.

Not available

S-EPMC8729058 | biostudies-literature

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Phase 1: Assessment of safety and tolerability of ADI-PEG 20 in combination with folinic acid (leucovorin), fluorouracil and oxaliplatin (FOLFOX) in advanced GI malignancies. Phase 2: Assessment of the objective response rate (ORR), measured by RECIST 1.1 criteria as assessed by blinded independent ...

2163812 | ecrin-mdr-crc

WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma.

Not available

S-EPMC9756969 | biostudies-literature

The plantlets of Populus treated with 20% (w/v) polyethylene glycol (PEG)6000 solution RNA-seq

PRJNA839878 | ENA

A phase 1 study of ADI-PEG 20 and modified FOLFOX6 in patients with advanced hepatocellular carcinoma and other gastrointestinal malignancies.

Not available

S-EPMC6850802 | biostudies-literature

Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.

Not available

S-EPMC4452427 | biostudies-literature