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ProteomicsTailoring an Intravenously Injectable Oncolytic Virus for Augmenting Radiotherapy
Oncolytic viruses (OVs) combined with radiotherapy (RT) have shown promise in clinical trials but remain limited by unsatisfactory efficacy. Key challenges include poor intravenous delivery, insufficient RT-induced DNA damage, and suboptimal anti-tumor immune responses. Herein, we developed a novel ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-02 | PXD060493 |
ProteomicsQuantitative proteomic atlas of phosphorylation and ubiquitination reveals Epn2-mediated endocytosis dysfunction in α-synuclein transgenic mice
Progression through neuronal loss of substantia nigra pars compacta with Parkinson’s disease depends on various protein post-translational modifications mainly comprising phosphorylation, ubiquitination, acetylation, and methylation. Phosphorylation and ubiquitination regulate major physiological ch...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-28 | PXD013965 | Pride
Phosphorylation Ubiquitination Parkinson’s disease Quantitative proteomics Endocytosis 
UnknownFamily shuffling of expandase genes to enhance substrate specificity for penicillin G.
Not available
S-EPMC522083 | biostudies-literature
UnknownComplete Taiwanese Macaque (Macaca cyclopis) Mitochondrial Genome: Reference-Assisted de novo Assembly with Multiple k-mer Strategy.
Not available
S-EPMC4488429 | biostudies-literature
UnknownA comparison of the molecular subtypes of triple-negative breast cancer among non-Asian and Taiwanese women.
Not available
S-EPMC5410215 | biostudies-literature
TranscriptomicsNeuroblastoma: MYCN normal vs. MYCN amplified
To evaluate the expression of genes associated with MYCN in NB, 10 tumors with MYCN amplification and 10 with normal MYCN copy number were subjected to oligonucleotide microarray using Agilent oligo microarray chips. Two-condition experiment, MYCN normal vs. MYCN amplified 10 NB patient tissues for ...
ORGANISM(S): Homo sapiens 
2013-12-17 | E-GEOD-53371 | biostudies-arrayexpress
UnknownA bibliometric analysis of 23,492 publications on rectal cancer by machine learning: basic medical research is needed.
Not available
S-EPMC7385823 | biostudies-literature
UnknownConduction system pacing upgrade versus biventricular pacing on pacemaker-induced cardiomyopathy: a retrospective observational study.
Not available
S-EPMC11300236 | biostudies-literature
UnknownHigh Frequency and Poor Outcome of Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia in Adults.
Not available
S-EPMC5455698 | biostudies-literature
UnknownCancer cell-derived immunoglobulin G activates platelets by binding to platelet FcγRIIa.
Not available
S-EPMC6349849 | biostudies-literature
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