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By employing a global gene expression profiling, we performed analysis of the molecular pathways which are deregulated in DU145 ALDH+ prostate cancer progenitors and DU145-RR radioresistant cells. Non-sorted, ALDH-negative, and ALDH-positive populations were analyzed, both for parental DU145 cell li...
ORGANISM(S): Homo sapiens 
A large body of evidence has demonstrated that many human tumors are maintained by a small cell population called cancer stem cells (CSCs) or tumor progenitors, which are responsible for tumor formation, therapy resistance and metastasis. We found that ionizing radiation treatment enriches for the C...
ORGANISM(S): Homo sapiens 
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