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TranscriptomicsRNA-seq of primary human bone marrow derived mesenchymal stromal cells from pediatric B-cell acute lymphoblastic leukemia (B-ALL) patients
To investigate the identity of the tumor microenvironment in acute lymphoblastic leukemia (B-ALL), the transcriptome of mesenchymal stromal cells derived from bone marrow of three pediatric patients at the onset of the disease was analyzed and compared with its normal counterpart.
ORGANISM(S): Homo sapiens 
2021-10-16 | E-MTAB-10838 | biostudies-arrayexpress
ModelsPro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia
Lineage fate decisions of hematopoietic cells depend on intrinsic factors and extrinsic signals provided by the bone marrow microenvironment, where they reside. Abnormalities in composition and function of hematopoietic niches have been proposed as key contributors of acute lymphoblastic leukemia (A...
4942 | Cell Collective
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