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TranscriptomicsEffects of the expression of M1775R and A1789T BRCA1 missense variants on the transcriptome of HeLa cells
BRCA1 (breast cancer 1, early onset) mutations confer a high breast and ovarian cancer risk. Most of BRCA1 cancer-predisposing mutations originate truncated proteins, but missense mutations have also been detected in familial breast and ovarian cancer patients. These variants are rare and their role...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-MTAB-761 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast transformed with five deleterious BRCA1 variants
In order to investigate the molecular mechanisms activated by deleterious BRCA1 variants in yeast, the RNA obtained from yeast cells transformed with five variants exhibiting a phenotypic effect, either on proliferation and/or on HR was hybridized on microarrays in comparison with the RNA from cells...
ORGANISM(S): Saccharomyces cerevisiae 
2009-03-31 | E-MEXP-1867 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat brain after prolonged administration of Phenytoin
In order to elucidate the molecular mechanisms of action of Phenytoin, we examined by microarrays the effects of prolonged administration of Phenytoin on gene expression in hippocampus and frontal cortex of Sprague-Dawley rats chronically treated with Phenytoin.
ORGANISM(S): Rattus norvegicus 
2009-12-31 | E-MEXP-1728 | biostudies-arrayexpress
UnknownPattern of comorbidities and 1-year mortality in elderly patients with COPD hospitalized in internal medicine wards: data from the RePoSI Registry.
Not available
S-EPMC7384278 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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