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MetabolomicsResting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α

Natural killer (NK) cells are forced to cope with different oxygen environments even under resting conditions. The adaptation to low oxygen is regulated by oxygen-sensitive transcription factors, the hypoxia-inducible factors (HIFs). The function of HIFs for NK cell activation and metabolic rewir...

2023-06-01 | MTBLS6863 | MetaboLights
UnknownUnderstanding physical literacy in the context of health: a rapid scoping review.
Not available
S-EPMC7570403 | biostudies-literature
UnknownEffects of flexible learning spaces, active breaks, and active lessons on sedentary behaviors, physical activity, learning, and musculoskeletal health in school-aged children: a scoping review.
Not available
S-EPMC11960325 | biostudies-literature
Genomicsexome_seq_hepatcell_adenomas - samples
Whole exome sequencing data from 30 donors (46 tumors and 30 non-tumoral whole exome sequencing, paired-end, HiSeq 2000, Illumina) collected by the Inserm U674, PI Jessica Zucman-Rossi - Institut National du Cancer (INCa), PI Fabien Calvo, France.
EGAD00001000737 | EGA
GenomicsEGAS00001001002 - samples
Description not provided
EGAD00001001096 | EGA
GenomicsEGAS00001000217 - samples
Genetic landscape of hepatocellular carcinoma
EGAD00001000131 | EGA
GenomicsExome-sequencing identifies new oncogenes and tumor suppressor genes recurrently altered in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. High-resolution copy number analysis of 125 tumors of which 24 were subjected to whole-exome sequencing identified 135 homozygous deletions and 994 somatic gene mutations with predicted functional consequences. We identified...
EGAS00001000217 | EGA
GenomicsIntegrative genomic profiling of hepatocellular adenomas reveals recurrent FRK activating mutations and mutational processes of malignant transformation
Hepatocellular adenomas (HCA) are benign liver tumors predominantly developed in women using oral contraception. Here, exome sequencing identified novel recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 activation and cell proliferation sensitive to Src inhibitors. We a...
EGAS00001000679 | EGA
GenomicsExome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Genomic analyses promise to improve tumor characterization in order to optimize personalized treatment for patients with hepatocellular carcinoma (HCC). Exome sequencing analysis of 243 liver tumors revealed mutational signatures associated with specific risk factors, mainly combined alcohol/tobacco...
EGAS00001001002 | EGA
ProteomicsGo_BioID_humancellmap_HEK293_highSDS_2019
This dataset consists of 404 raw MS files and associated peak lists and result files, acquired on Velos Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode. All samples are BioID experiments, performed in HEK293 Flp-In T-REx cells from organellar and other subcellular marke...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000084360 | MassIVE
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