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TranscriptomicsTwo different 4-week energy-restricted diets.
The main aim of this experiment was to investigate gene expression on human adipose tissue after two different 4-week energy-restricted diets. Our questions consisted in understanding how gene expression was linked to clinical parameters of obese patients and whether the two diets were discriminated...
ORGANISM(S): Homo sapiens 
2011-02-09 | E-GEOD-27121 | biostudies-arrayexpress
TranscriptomicsCardiac aldosterone regulated genes in mice
Aldosterone excess is involved in cardiac diseases. The mechanisms are still unclears. Mice were treated for 7 days with aldosterone and a whole genome microarray analysis was performed. Two-group experiment: Untreated mice (Ctrl), mice + aldosterone treatment (Aldo). One comparisons: Ctrl vs Aldo
ORGANISM(S): Mus musculus 
2016-09-08 | E-GEOD-50709 | biostudies-arrayexpress
MetabolomicsA data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity
The mechanisms responsible for weight loss-induced improvement in insulin sensitivity are partially understood. Greater insight can now be achieved through deep phenotyping and data integration. Here, we used an integrative approach to investigate associations between changes in insulin sensitivity ...
2021-02-11 | MTBLS653 | MetaboLights
TranscriptomicsSubcutaneous adipose tissue from lean and obese subjects
Obtaining adipose tissue samples are paramount to the understanding of human obesity. We have examined the impact of needle-aspirated and surgical biopsy techniques on the study of subcutaneous adipose tissue (scAT) gene expression in both obese and lean subjects. Biopsy sampling methods have a sign...
ORGANISM(S): Homo sapiens 
2008-12-22 | E-GEOD-12050 | biostudies-arrayexpress
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