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ProteomicsIdentification of post-translational modifications on soluble alpha-Synuclein purified from various alpha-Synucleinopathies by LC-MSMS
LC-MS/MS analyses were performed on soluble alpha-Syn purified from PD and various alpha-Synucleinopathies to systematically explore the landscape of post-translational modifications (PTMs) on soluble alpha-Syn, leading to the identification of a large number of novel alpha-Syn PTMs.
ORGANISM(S): Homo sapiens (Human) 
2023-02-02 | PXD037994 | Pride
Human Post-translational modification Brain Soluble a-synuclein Alpha-synucleinopathies 
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
UnknownChemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis.
Not available
S-EPMC4410955 | biostudies-literature
UnknownGrowth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells.
Not available
S-EPMC5000754 | biostudies-literature
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
UnknownSpatial-temporal patterns of brain disconnectome in Alzheimer's disease.
Not available
S-EPMC10318207 | biostudies-literature
ProteomicsDIA-Based Quantitative Proteomics Analysis of Human Gastric Cancer Cells
This study investigates the proteomic landscape of AGS gastric cancer cells with stable overexpression of the VASN gene. Utilizing DIA-based quantitative proteomics, we examined protein expression changes in VASN-overexpressing AGS cells compared to their negative control (NC) counterparts. The resu...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD058610 | Pride
Cell Dia Gastric Human 
UnknownResponse Characteristics of Nitrifying Bacteria and Archaea Community Involved in Nitrogen Removal and Bioelectricity Generation in Integrated Tidal Flow Constructed Wetland-Microbial Fuel Cell.
Not available
S-EPMC7324634 | biostudies-literature
UnknownClinical Application of Ultraviolet C Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 in Contaminated Hospital Environments.
Not available
S-EPMC8706350 | biostudies-literature
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