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GenomicsGenome-wide ChIP-seq analysis of Pou3f1 during mouse pluripotent stem cell neural fate commitment
Appropriate neural initiation of the pluripotent stem cells in the early embryos is critical for the development of the central nervous system. This process is regulated by the coordination of extrinsic signals and intrinsic programs. However, how the coordination is achieved to ensure proper neural...
ORGANISM(S): Mus musculus 
2015-11-23 | E-GEOD-69778 | biostudies-arrayexpress
TranscriptomicsAnalysis of Transcriptome Complexity via RNA-Seq in Normal and Failing Murine Hearts
Accurate and comprehensive de novo transcriptome profiling in heart is a central issue to better understand cardiac physiology and diseases. Although significant progress has been made in genome-wide profiling for quantitative changes in cardiac gene expression, current knowledge offers limited insi...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-29446 | biostudies-arrayexpress
TranscriptomicsStereo-sequencing: 3D Transcriptome of the mouse embryo at gastrulation
To glean an appreciation of the holistic genetic activity in the gastrulating mouse embryo, we performed a genome-wide spatial transcriptome analysis (Stereo-seq), using a low-cell number sequencing protocol on laser microdissected samples of epiblast cells with retained positional address. The 3D t...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-65924 | biostudies-arrayexpress
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