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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
TranscriptomicsTranscriptome analysis of L-form, protoplast of the B. subtilis cells
To investigate whether the oxidative stress response is induced in protoplasts, we compared the gene expression patterns of protoplasts to those of walled cells and L-forms using microarrays.
ORGANISM(S): Bacillus subtilis 
2015-04-15 | E-MTAB-3380 | biostudies-arrayexpress
ProteomicsIntegrative Proteome and Metabolomics Analyses of Cryptococcus neoformans Responses to Melanin Substrates Niger seed and L-DOPA
Melanin, as a pivotal antioxidant pigment, plays a critical role in the pathogenicity of Cryptococcus neoformans. However, the underlying signaling pathways responsible for melanin biosynthesis in C. neoformans are not yet fully elucidated. In this study, proteome and metabolomics analyses were cond...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2025-07-23 | PXD056054 | Pride
Cryptococcus neoformans  melanin biosynthesis  substrate-dependent manner  substrate-independent manner 
MetabolomicsUntargeted plasma metabolome identifies biomarkers in patients with extracranial arteriovenous malformations

OBJECTIVE: This study aimed to investigate the plasma metabolic profile of patients with extracranial arteriovenous malformations (AVM).

METHOD: Plasma samples were collected from 32 AVM patients and 30 healthy controls (HC). Ultra-high performance liquid c...

2023-10-30 | MTBLS7753 | MetaboLights
MetabolomicsElevated temperature accelerates leaf senescence and promotes leaf nitrogen transport to improve rice grain protein synthesis
Elevated temperatures during grain filling severely constrain rice yield and quality. Although additional nitrogen can mitigate the adverse effects of elevated temperature, both factors increase grain protein content, and the underlying physiological mechanisms remain poorly understood. Here, we con...
2026-06-17 | MTBLS14777 | MetaboLights
UnknownExogenous L-Serine Alleviates <i>Pasteurella multocida</i>-Induced Inflammation by Reprogramming the Transcription and Metabolism of Macrophages.
Not available
S-EPMC11945856 | biostudies-literature
UnknownExogenous L-Alanine promotes phagocytosis of multidrug-resistant bacterial pathogens
Not available
S-SCDT-10_15252-EMBR_201949561 | biostudies-other
TranscriptomicsTriticum aestivum strain:cultivar Transcriptome or Gene expression
The pistillody mutant wheat (Triticum aestivum L.) plant HTS-1 exhibits homeotic transformation of stamens into pistils or pistil-like structures. Unlike common wheat varieties, HTS-1 produces three to six pistils per floret, potentially increasing the yield. Thus, HTS-1 is highly valuable in the st...
ORGANISM(S): Triticum aestivum 
2014-03-14 | E-MTAB-4469 | biostudies-arrayexpress
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