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MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
UnknownFusarium Mycotoxins and OTA in Beer from Shanghai, the Largest Megacity in China: Occurrence and Dietary Risk Assessment.
Not available
S-EPMC10452965 | biostudies-literature
UnknownA comparative study on photosynthetic characteristics and flavonoid metabolism between Camellia petelotii (Merr.) Sealy and Camellia impressinervis Chang &Liang.
Not available
S-EPMC9762238 | biostudies-literature
Transcriptomicsp53 prevents neurodegeneration by regulating synaptic genes
DNA damage has been implicated in neurodegenerative disorders, including Alzheimer’s disease and other tauopathies, but the consequences of genotoxic stress to postmitotic neurons are poorly understood. Here we demonstrate that p53, a key mediator of the DNA damage response, plays a neuroprotective ...
ORGANISM(S): Drosophila melanogaster 
2015-01-06 | E-GEOD-40418 | biostudies-arrayexpress
TranscriptomicsThe MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila
Active genes on the X chromosome of Drosophila males are upregulated by the Male-specific lethal (MSL) complex containing five MSL proteins and two non-coding roX RNAs. To probe the targeting mechanism, we have solved the structure of the MSL3 chromodomain, designed point mutations in key residues t...
ORGANISM(S): Drosophila melanogaster 
2008-11-18 | E-GEOD-11817 | biostudies-arrayexpress
UnknownIntroducing π-HelixNovo for practical large-scale de novo peptide sequencing.
Not available
S-EPMC10858680 | biostudies-literature
UnknownBiostable L-DNAzyme for Sensing of Metal Ions in Biological Systems.
Not available
S-EPMC4892185 | biostudies-literature
UnknownA tyrosine aminotransferase involved in rosmarinic acid biosynthesis in Prunella vulgaris L.
Not available
S-EPMC5501851 | biostudies-literature
UnknownBacterial c-di-GMP signaling gene affects mussel larval metamorphosis through outer membrane vesicles and lipopolysaccharides.
Not available
S-EPMC10994910 | biostudies-literature
TranscriptomicsInhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21 [Gene expression]
The epidemiologic association between statin use and decreased risk of advanced prostate cancer suggests that statins may inhibit prostate cancer development and/or progression. Studies were performed to determine the effects of a model statin, atorvastatin (ATO), on the proliferation and different...
ORGANISM(S): Homo sapiens 
2013-09-30 | E-GEOD-46374 | biostudies-arrayexpress
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