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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
TranscriptomicsTranscription profiling of human cells expressing FoxM1-ER fusion protein
Experiment description To identify FoxM1-regulated genes, we carried out gene expression profile analysis after inducible activation of a FoxM1-ER fusion protein using high-density human cDNA microarrays. We constructed a stable line of U2OS cells expressing full-length HA-FoxM1 fused at its C-term...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-230 | biostudies-arrayexpress
UnknownInvestigating Dynamic Interdomain Allostery in Pin1.
Not available
S-EPMC4610412 | biostudies-literature
TranscriptomicsMouse feeding experiment
Mice used in this study were 129/sv males, 8-15 weeks of age, which were housed individually and received water ad libitum. Normal fed animals were fed before and during the 48h experiment with standard food ad libitum. Sugar fed animals were fed before the experiment with standard food ad libitum a...
ORGANISM(S): Mus musculus 
2004-02-08 | E-GEOD-858 | biostudies-arrayexpress
ProteomicsThe Extreme Halophilic Archaeon Haloferax volcanii Reduced Fe(III) to Conserve Energy from Extracellular Electron Transfer
Iron availability affects oceanic primary productivity and the strength of the biological carbon pump. However, the mechanism of iron solubility in hypersaline environments is poorly understood. In this work, we investigated the extremely halophilic archaeon Haloferax volcanii to reduce ferrihydrite...
ORGANISM(S): Haloferax Volcanii 
2026-02-08 | PXD074223 |
UnknownStomatal responses of terrestrial plants to global change.
Not available
S-EPMC10110556 | biostudies-literature
Genomicsena-DATASET-DUKE-NUS-01-04-2016-09:56:06:868-175 - samples
CCA targeted sequencing
EGAD00001001994 | EGA
Genomicsena-DATASET-DUKE-NUS-28-03-2016-04:29:04:072-192 - samples
Cholangiocarcinoma whole genome sequencing data
EGAD00001001988 | EGA
Genomicsena-DATASET-DUKE-NUS-05-12-2017-07:28:25:856-358 - samples
This dataset contains whole genome sequencing FASTQ data for 12 cholangiocarcinoma tumor samples, and their matched normal samples. These 12 samples are in addition to 59 samples available in dataset EGAD00001001988, and consist of patients from Thailand, Romania, and Singapore. Paired-end sequencin...
EGAD00001003834 | EGA
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