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TranscriptomicsTumor grafts derived from patients with head and neck squamous carcinoma.
Head and neck squamous cell carcinoma (HNSCC) is a deadly and disfiguring disease for which better systemic therapy is desperately needed. The development of new therapies for HNSCC and the understanding of its biology both depend upon clinically relevant animal models. An increasingly promising x...
ORGANISM(S): Homo sapiens 
2013-10-28 | E-GEOD-45153 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of PIK3CA knockdown by shRNA in lung cancer cells
To gain insight into EMT-independent biological processes through which PI3K promotes invasion, RNA samples from 344SQ_p110α shRNA cells and 344SQ_scr cells were subjected to global transcriptional profiling. Two groups, control and PIK3CA shRNA, in 344SQ lung cancer cell line Two group comparison
ORGANISM(S): Mus musculus 
2014-05-02 | E-GEOD-46869 | biostudies-arrayexpress
ProteomicsA Pandas complex adapted for piRNA-guided transposon silencing and heterochromatin formation
dNxf2 directly interacts with dNxf1 to compete with its binding to NPC
ORGANISM(S): Drosophila Melanogaster 
2019-08-01 | PXD014884 |
ProteomicsA Pandas complex adapted for piRNA-guided transposon silencing and heterochromatin formation, Panx-IP-MS
The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In Drosophila ovaries, Panoramix (Panx) enforces transcriptional silencing by binding to the target-engaged Piwi-piRNA complex, although the precise mechanisms by which this occurs re...
ORGANISM(S): Drosophila Melanogaster 
2019-08-06 | PXD014926 |
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