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Transcriptomicsc-Myc binding in HL60 cells
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Characterization of c-Myc binding in HL60 cells. Thirteen biologically independent replicates of growing HL60 cells were subjected to ChIP with an N-terminal c-Myc antibod...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-8447 | biostudies-arrayexpress
TranscriptomicsCharacterization of technical variation in ChIP-on-chip studies
Analysis of technical variance of ChIP-on-Chip studies by characterization of Myc-binding in HL60 cells. Keywords: Chip-on-chip Fully-blocked study of technical variance in Myc-binding in HL60 cells. Two different antibodies were used to generate 6 biologically independent replicates each. Each repl...
ORGANISM(S): Homo sapiens 
2008-10-31 | E-GEOD-8448 | biostudies-arrayexpress
TranscriptomicsComparison of genomic DNA amplification methods
Hybridization of amplified genomic DNA against unamplified genomic DNA using three different amplification methods to assess the bias introduced by amplification alone. Keywords: genomic DNA Three different amplification methods were assessed and total genomic DNA hybridized against equal amounts of...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-8449 | biostudies-arrayexpress
UnknownEffect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial.
Not available
S-EPMC9707833 | biostudies-literature
TranscriptomicsA systematic evaluation of pattern discovery algorithms
Pattern discovery algorithms are methods for discovering recurrent, non-random motifs widely used in the analysis of biological sequences. Many algorithms exist but few comparisons have been made amongst them. We systematically profile eight representative methods at multiple parameter settings acro...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-15370 | biostudies-arrayexpress
UnknownCo-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction.
Not available
S-EPMC5216778 | biostudies-literature
TranscriptomicsTranscription profiling of human aortic smooth muscle cells exposed to hypoxia
Systemic arterial smooth muscle cells are exposed to a broad range of oxygen concentrations under physiological conditions. Hypoxia can modulate the proliferative response of smooth muscle cells leading to speculation about its role in vasculogenesis, vascular remodelling and the pathogenesis of ar...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4725 | biostudies-arrayexpress
TranscriptomicsGenome-wide characterization of the transcriptional program of Myc-dependent transformation, expression study
We profiled Myc binding in a normal breast cell-line (MCF10A) under basal conditions after ectopic expression of Myc. We showed that ectopic Myc expression increases tumour formation in vivo and in vitro. We then profiled genome-wide Myc binding using Agilent promoter arrays in MCF10A cells expressi...
ORGANISM(S): Homo sapiens 
2009-11-24 | E-GEOD-14263 | biostudies-arrayexpress
TranscriptomicsDetermining lovastatin-induced differences in expression between statin sensitive and insensitive MM cells
The goals of this study were to determine global differences in transcript expression and regulation between MM cells that are sensitive or insensitive to lovastatin-induced apoptosis. To this end, two sensitive (KMS11 and H929) and two insensitive (LP1 and SKMM1) MM cell lines treated with 20uM lo...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-15946 | biostudies-arrayexpress
TranscriptomicsIdentifying chromatin associations with promyelocytic leukemia nuclear bodies using immunoTRAP
Studies using fluorescence in situ hybridization (FISH) have attempted to determine whether specific gene loci associate with promyelocytic leukemia nuclear bodies (PML NBs). Two drawbacks accompany this approach; the lack of spatial resolution inherent with the technique, and the a priori basis fo...
ORGANISM(S): Homo sapiens 
2013-03-28 | E-GEOD-40554 | biostudies-arrayexpress
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