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ProteomicsThe APC/C activator Cdh1p plays a role in mitochondrial metabolic remodelling in yeast
Cdh1p is one of the two substrate adaptor proteins of the anaphase promoting complex/cyclosome (APC/C), an ubiquitin ligase that regulates proteolysis during cell cycle. In this work, using a proteomic approach, we found 135 mitochondrial proteins whose abundance was significantly altered in the cdh...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-02-24 | PXD039879 | Pride
Proteomics Yeast Mitochondria Yap1p Cdh1p 
UnknownIn women with previous pregnancy hypertension, levels of cardiovascular risk biomarkers may be modulated by haptoglobin polymorphism.
Not available
S-EPMC4102073 | biostudies-literature
TranscriptomicsGene expression data from phosphinothricin (PPT) treated Medicago truncatula root nodules
Nitrogen assimilation in plants is a tightly regulated process that integrates developmental and environmental signals. The legume-rhizobial symbiosis results in the formation of a specialized organ called root nodule, where the rhizobia fixes atmospheric nitrogen into ammonia. Ammonia is assimilate...
ORGANISM(S): Medicago truncatula 
2012-05-08 | E-GEOD-34155 | biostudies-arrayexpress
MetabolomicsIntegration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a cohort of 42 subjects with different levels of glucose tolerance (...
2020-01-06 | MTBLS1051 | MetaboLights
TranscriptomicsExpression profiles of the hippocampus of Rsk2-KO mice
Coffin–Lowry Syndrome (CLS) is a syndromic form of mental retardation caused by loss of function mutations in the X-linked RPS6KA3 gene, which encodes Rsk2, a serine/threonine kinase involved in spatial memory. We analyzed hippocampal gene expression profiles in Rsk2-KO mice to identify changes in ...
ORGANISM(S): Mus musculus 
2010-12-22 | E-GEOD-22137 | biostudies-arrayexpress
UnknownDNA Double-Strand Breaks Induced in Human Cells by Twelve Metallic Species: Quantitative Inter-Comparisons and Influence of the ATM Protein.
Not available
S-EPMC8533583 | biostudies-literature
UnknownCopy Number Profiling of Brazilian Astrocytomas.
Not available
S-EPMC4938641 | biostudies-literature
TranscriptomicsGene expression during early stages of arbuscular mycorrhizal root formation in Medicago truncatula.
Arbuscular mycorrhiza (AM) interactions between plants and Glomeromycota fungi primarily support phosphate aquisition of most terrestrial plant species. To unravel gene expression during early stages of Medicago truncatula root colonization by AM fungi, we used genome-wide transcriptome profiling ba...
ORGANISM(S): Medicago truncatula 
2012-03-27 | E-GEOD-34617 | biostudies-arrayexpress
TranscriptomicsGene expression data from arbuscular mycorrhizal and phosphate-treated Medicago truncatula roots.
Arbuscular mycorrhiza (AM) interactions between plants and Glomeromycota fungi primarily support phosphate aquisition of most terrestrial plant species. To unravel gene expression in Medicago truncatula root colonization by AM fungi, we used genome-wide transcriptome profiling based on whole mycorrh...
ORGANISM(S): Medicago truncatula 
2011-10-28 | E-GEOD-32208 | biostudies-arrayexpress
TranscriptomicsCell- and tissue-specific transcriptome analyses of Medicago truncatula root nodules
We used laser-capture microdissection (LCM) to isolate specific cells from the Medicago truncatula nodule meristem (M), the distal infection (DIZ), the proximal infection zone (PIZ), infected cells (IC) and uninfected cells (UIC) from the fixation zone. Based on Medicago GeneChips, we identified the...
ORGANISM(S): Medicago truncatula 
2013-05-29 | E-GEOD-43354 | biostudies-arrayexpress
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