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MetabolomicsMass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50-80% patients exhibiting mutations in the von Hippel-Lindau (VHL) gene. RSUME (RWD domain (termed after three major RWD-containing proteins: RING finger-containing proteins, WD-repeat-containing proteins, and yeast DEAD (DEXD)...
2021-10-06 | MTBLS1935 | MetaboLights
UnknownA Population-Based Study of Diabetes During Pregnancy in Spain (2009-2015): Trends in Incidence, Obstetric Interventions, and Pregnancy Outcomes.
(1) Background: We examined trends in incidence and outcomes in women with existing type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) compared with a control group without diabetes. (2) Methods: This was an observational, retrospective epidemiol...
S-EPMC7074053 | biostudies-literature
UnknownAutonomous electrochemical system for ammonia oxidation reaction measurements at the International Space Station.
An autonomous electrochemical system prototype for ammonia oxidation reaction (AOR) measurements was efficiently done inside a 4'' x 4'' x 8'' 2U Nanoracks module at the International Space Station (ISS). This device, the Ammonia Electrooxidation Lab at the ISS (AELISS), included an autonomous elect...
S-EPMC9995563 | biostudies-literature
UnknownAcute stress of the healthcare workforce during the COVID-19 pandemic evolution: a cross-sectional study in Spain.

Objectives

To determine the volume of health professionals who suffered distress due to their care of patients with COVID-19 and to analyse the direction in which the response capacity of the professionals to face future waves of COVID-19 is evolving.

Design

A cross-sectional study.
S-EPMC7650075 | biostudies-literature
UnknownModelling the potential clinical and economic impact of universal immunisation with nirsevimab versus standard of practice for protecting all neonates and infants in their first respiratory syncytial virus season in Spain.

Background

Respiratory syncytial virus (RSV) is associated with substantial morbidity among infants. This study modelled the potential public health and economic impact of nirsevimab, a long-acting monoclonal antibody, as an immunoprophylactic strategy for all infants in Spain in their first...
S-EPMC11378427 | biostudies-literature
UnknownEstimation of Admission D-dimer Cut-off Value to Predict Venous Thrombotic Events in Hospitalized COVID-19 Patients: Analysis of the SEMI-COVID-19 Registry.

Background

Venous thrombotic events (VTE) are frequent in COVID-19, and elevated plasma D-dimer (pDd) and dyspnea are common in both entities.

Objective

To determine the admission pDd cut-off value associated with in-hospital VTE in patients with COVID-19.

Methods

Multicenter, ...
S-EPMC8294343 | biostudies-literature
UnknownEffectiveness and safety of first-generation protease inhibitors in clinical practice: Hepatitis C virus patients with advanced fibrosis.

Aim

To evaluates the effectiveness and safety of the first generation, NS3/4A protease inhibitors (PIs) in clinical practice against chronic C virus, especially in patients with advanced fibrosis.

Methods

Prospective study and non-experimental analysis of a multicentre cohort of 38 Sp...
S-EPMC4533049 | biostudies-literature
UnknownOptimizing Mandibular Advancement Maneuvers during Sleep Endoscopy with a Titratable Positioner: DISE-SAM Protocol.
Mandibular advancement devices (MAD) are an effective alternative treatment to CPAP. Different maneuvers were performed during drug sleep-induced endoscopy (DISE) to mimic the effect of MAD. Using the Selector Avance Mandibular (SAM) device, we aimed to identify MAD candidates during DISE using a ti...
S-EPMC8836970 | biostudies-literature
UnknownThe role of gender in a smoking cessation intervention: a cluster randomized clinical trial.

Background

The prevalence of smoking in Spain is high in both men and women. The aim of our study was to evaluate the role of gender in the effectiveness of a specific smoking cessation intervention conducted in Spain.

Methods

This study was a secondary analysis of a cluster randomize...
S-EPMC3125366 | biostudies-literature
Unknown<i>Pyricularia pennisetigena and Pyricularia oryzae</i> isolates from Paraguay's wheat-growing regions and the impact on wheat.
The Pyricularia genus includes species causing blast disease in monocots, posing significant challenges for disease management due to their ability to infect multiple hosts. This study aimed to identify the pathogenicity and species identity of Pyricularia isolates from 11 plant specie...
S-EPMC11919303 | biostudies-literature
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