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GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
TranscriptomicsshRNA profiling of mouse erythroleukemia (MEL) cells and their corresponding G9a knock downs reveals a dual role for the methyltransferase G9a in the maintenance of beta-globin gene expression
MEL clone 745 cells that are blocked at the pro-erythroblast stage serve as a model for terminal erythroid differentiation when treated with DMSO. A stable MEL cell line expressing (Dox)-dependent shRNA sequence targeting different regions of G9a mRNA was established and screened as previously desc...
ORGANISM(S): Mus musculus 
2009-11-09 | E-GEOD-15620 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
An 11-point time course study comparing V6.5 embryonic stem cells versus embryoid bodies. Time course 0 hours, 6 hours, 12 hours, 18 hours, 24 hours, 36 hours, 48 hours, 4 days, 7 days, 9 days, and 14 days. Experiment Overall Design: this experiment include 11 samples and 66 replicates
ORGANISM(S): Mus musculus 
2007-12-18 | E-GEOD-3231 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
An 11-point time course study on differentiating embryoid bodies from a murine J1 embryonic stem cell line. The time course includes 0 hr, 6 hr, 12 hr, 18 hr, 24 hr, 36 hr, 48 hr, 4 days, 7 days, 9 days and 14 days. Experiment Overall Design: this experiment includes 11 samples and 66 replicates.
ORGANISM(S): Mus musculus 
2007-12-14 | E-GEOD-3749 | biostudies-arrayexpress
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