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TranscriptomicsPeriostin
We compared transcriptional differences between Periostin siRNA treated and GFP-siRNA treated in OP9 cells using Affymetrix mouse 430_2 array.
ORGANISM(S): Mus musculus 
2012-01-26 | E-MTAB-519 | biostudies-arrayexpress
TranscriptomicsPeriostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor invasive signature in esophageal cancer
Human squamous cell cancers are the most common epithelially derived malignancies. One example is esophageal squamous cell carcinoma (ESCC), which is associated with a high mortality rate that is related to a propensity for invasion and metastasis. We report that periostin, a highly expressed cell a...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-21293 | biostudies-arrayexpress
TranscriptomicsExpression data from mice brain implanted GSC272 glioma stem cells or POSTN knockout
Differential mRNA expression patterns were seen in GSC272-vector compared to GSC272-POSTN shRNA tumors. We used microarrays to POSTN regulated gene expression in glioma stem cells. Gene expression comparisons were shown between: 1. mRNA control from GSC272 glioma stem cells implanted mouse brain tum...
ORGANISM(S): Homo sapiens 
2015-09-16 | E-GEOD-73071 | biostudies-arrayexpress
UnknownPeriostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models.
Not available
S-EPMC5104278 | biostudies-literature
Unknownp73 promotes glioblastoma cell invasion by directly activating POSTN (periostin) expression.
Not available
S-EPMC4914248 | biostudies-literature
TranscriptomicsThe immunomodulatory effects of periostin on monocyte-derived macrophages
To explore the effects of periostin on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. In the absen...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70821 | biostudies-arrayexpress
TranscriptomicsPeriostin cooperates with mutant p53 to mediate invasion
Periostin, a matricellular protein, has been reported to be important in supporting tumor cell dissemination. However, the molecular mechanisms underlying periostin function within the tumor microenvironment are poorly understood. In this study, we observe that loss of periostin decreases esophageal...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-48999 | biostudies-arrayexpress
ProteomicsMonocyte histone lactylation-regulated exosomal periostin promotes retinal neovascularization
Exosomes serve as signaling messengers that facilitate intercellular communication through delivering molecular cargo. Here, we observed elevated levels of exosomal periostin (POSTN) in blood plasma of patients with proliferative diabetic retinopathy (PDR). Monocytes-derived exosomal POSTN was incre...
ORGANISM(S): Homo Sapiens 
2025-01-20 | PXD059956 |
ProteomicsDevelopment of a top-down MS assay for specific identification of human periostin isoforms
Periostin is a matricellular protein encoded by the POSTN gene that is alternatively spliced to produce ten different isoforms of periostin with a molecular weight ranging from 78 to 91 kDa. Periostin is known to promote fibrillogenesis, organize the extracellular matrix, and bind integrin-receptors...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2024-06-11 | PXD045560 | Pride
Alternative splicing Top down ms Periostin Proteoforms 
UnknownPeriostin modulates extracellular matrix behavior in tendons.
Not available
S-EPMC9673102 | biostudies-literature
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