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TranscriptomicsSuppression of p53-mediated senescence by non-canonical NF-kappaB pathway mediated regulation of EZH2 expression
The NF-kappaB and p53 transcription factors control the expression of complex gene regulatory networks in response to many cell stresses and stimuli. This experiment describes gene expression profiling of cells depleted for EZH2, NF-kappaB2, RelB and p53. We find that EZH2 is the major effector of c...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-MTAB-1593 | biostudies-arrayexpress
UnknownCohort profile: the BABY1000 pilot prospective longitudinal birth cohort study based in Sydney, Australia.
Not available
S-EPMC10255277 | biostudies-literature
UnknownShort chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver.
Not available
S-EPMC4772307 | biostudies-literature
TranscriptomicsPositive and negative regulation of lymphomagenesis by the NF-kappaB subunit c-Rel
'The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour promoting transcription factor. Here we report the surprising result that c-rel -/- mice display significantly earlier lymphomagenesis in the c-Myc driven, Eμ-Myc model of B-cell lym...
ORGANISM(S): Mus musculus 
2014-12-31 | E-MTAB-2774 | biostudies-arrayexpress
UnknownMeasuring the Impact of Quantitative Information on Patient Understanding: Approaches for Assessing the Adequacy of Patient Knowledge about Colorectal Cancer Screening.
Not available
S-EPMC9703495 | biostudies-literature
UnknownIdentification of Potential Serum Protein Biomarkers and Pathways for Pancreatic Cancer Cachexia Using an Aptamer-Based Discovery Platform.
Not available
S-EPMC7765482 | biostudies-literature
ProteomicsProteome wide measurements of protein half-lives in Mycoplasma pneumoniae
We obtained proteome wide measurements of protein half-lives in M. pneumoniae by performing pulse-chase experiments following SILAC methods. We estimated degradation rates of individual proteins by measuring the increase in light protein compared to heavy protein labeling along the growth curve.
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2020-11-24 | PXD016386 | Pride
Degradation rates Protein half-life Silac 
UnknownImmunomodulation by Entinostat in Renal Cell Carcinoma Patients Receiving High-Dose Interleukin 2: A Multicenter, Single-Arm, Phase I/II Trial (NCI-CTEP#7870).
Not available
S-EPMC5712266 | biostudies-literature
UnknownA phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer.
Not available
S-EPMC7826483 | biostudies-literature
UnknownRandomized phase II study of consolidation immunotherapy with nivolumab and ipilimumab or nivolumab alone following concurrent chemoradiotherapy for unresectable stage IIIA/IIIB non-small-cell lung cancer (NSCLC): Big Ten Cancer Research Consortium LUN16-081.
Not available
S-EPMC12265819 | biostudies-literature
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