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TranscriptomicsCooler temperatures destabilize RNA interference and increase susceptibility of disease vector mosquitoes to viral infection
The impact of global climate change on the transmission dynamics of infectious diseases is the subject of extensive debate. The transmission of mosquito-borne viral diseases is particularly complex, with climatic variables directly affecting many parameters associated with the prevalence of disease ...
ORGANISM(S): Aedes albopictus 
2013-08-13 | E-GEOD-46204 | biostudies-arrayexpress
GenomicsIntegrative Analyses of Gene Expression and DNA Methylation Profiles in a Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate a Crucial Role of Cells with Stem-like Properties
Purpose: Development of resistance to tamoxifen is an important clinical issue in the treatment of patients with breast cancer. Tamoxifen resistance may be the result of the acquisition of epigenetic regulation such as DNA methylation within breast cancer cells resulting in changed mRNA expression o...
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-40665 | biostudies-arrayexpress
UnknownGilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations.
Not available
S-EPMC7013266 | biostudies-literature
UnknownThe impact of FLT3 mutation clearance and treatment response after gilteritinib therapy on overall survival in patients with FLT3 mutation-positive relapsed/refractory acute myeloid leukemia.
Not available
S-EPMC7897940 | biostudies-literature
UnknownMolecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib.
Not available
S-EPMC9006281 | biostudies-literature
TranscriptomicsDesign and testing of genome-proxy microarrays to profile marine microbial communities
Microarrays are useful tools for detecting and quantifying specific functional and phylogenetic genes in natural microbial communities. In order to track uncultivated microbial genotypes and their close relatives in an environmental context, we designed and implemented a “genome proxy” microarra...
ORGANISM(S): marine metagenome 
2010-05-25 | E-GEOD-9384 | biostudies-arrayexpress
UnknownA next-generation sequencing-based assay for minimal residual disease assessment in AML patients with FLT3-ITD mutations.
Not available
S-EPMC5916006 | biostudies-literature
UnknownSelective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study.
Not available
S-EPMC5572576 | biostudies-literature
UnknownN95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial.
Not available
S-EPMC6724169 | biostudies-literature
UnknownPharmacokinetic Profile of Gilteritinib: A Novel FLT-3 Tyrosine Kinase Inhibitor.
Not available
S-EPMC7550323 | biostudies-literature
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