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ProteomicsMitochondria drive a folate-based immunity against an intracellular pathogen
As major consumers of cellular metabolites, mitochondria are poised to compete with invading microbes for the nutrients they need to grow. Yet, whether cells weaponize mitochondrial metabolism during infection remains poorly understood. We found that the transcription factor ATF4 activates a mitocho...
ORGANISM(S): Homo sapiens (Human) Toxoplasma gondii GT1 
2025-10-02 | PXD064338 | Pride
Mitochondria Tmt 
TranscriptomicsAnalysis of impact of Toxoplasma effector MAF1 during Type II infection in WT MEFs and during Type I infection in WT and MAVS KO MEFs
The goals of the microarray experiment were to determine the role of MAF1, the Toxoplasma gondii mediator of host mitochondrial association, on host cell gene expression by comparing infection of WT cells with Type II and Type II:MAF1 parasites. We also explored the role of MAF1 on host cell gene ex...
ORGANISM(S): Mus musculus 
2014-01-23 | E-GEOD-54285 | biostudies-arrayexpress
UnknownGlutamine sensing licenses cholesterol synthesis
Not available
S-SCDT-10_1038-S44318-024-00269-0 | biostudies-other
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