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Antimalarial peroxides such as the phytochemical artemisinin or the synthetic artefenomel are activated by reductive cleavage of the peroxide bond. This happens inside the malaria parasite, presumably in the food vacuole with ferrous heme as the electron donor. The generated carbon-centered radicals...
ORGANISM(S): Plasmodium falciparum NF135/5.C10 
2022-02-24 | PXD010264 | Pride
Candida albicans pathways that protect against organic peroxides and lipid peroxidation.
Human fungal pathogens must survive diverse reactive oxygen species (ROS) produced by host immune cells. ROS can oxidize a range of cellular molecules including proteins, lipids, and DNA. Formation of lipid radicals by ROS can be especially damaging, as it leads to a chain reaction of lipid peroxida...
ORGANISM(S): Candida albicans 
2024-09-20 | GSE275502 | GEO
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