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TranscriptomicsWnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl
Although Bcr-Abl kinase inhibitors have proven effective in the treatment of chronic myeloid leukemia (CML), they generally fail to completely eradicate Bcr-Abl+ leukemia cells. To identify genes whose inhibition sensitizes Bcr-Abl+ leukemias to killing by Bcr-Abl inhibitors, we performed an RNAi-ba...
ORGANISM(S): Homo sapiens 
2010-07-15 | E-GEOD-21499 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of human multiple myloma p53 wild type cells treated with nutlin 3A
The miRNA profiles were analyzed for nutlin 3A treated and untreated multiple myloma p53 wild type cells
ORGANISM(S): Homo sapiens 
2010-07-22 | E-TABM-1038 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of human multiple myloma cell lines with or without p53 mutations
The miRNA profiles were analyzed for 6 multiple myloma cell lines with or without p53 mutations, in duplicate
ORGANISM(S): Homo sapiens 
2010-07-22 | E-TABM-1037 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of acute myeloid leukemia patient samples for analysis of KIT and SP1 expression
Oligonucleotide expression microarray data used for analysis of KIT and SP1 expression levels in AML patient samples
ORGANISM(S): Homo sapiens 
2011-03-16 | E-TABM-945 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of acute myeloid leukemia patient samples for analysis of miR-29b expression
microRNA microarray data used for analysis of miR-29b expression in AML patient samples
ORGANISM(S): Homo sapiens 
2011-03-16 | E-TABM-944 | biostudies-arrayexpress
TranscriptomicsLenalidomide-mediated enhanced translation of C/EBP?-p30 protein upregulates expression of the anti-leukemic microRNA-181a in acute myeloid leukemia - microRNA Data
Recently, we showed that increased miR-181a expression was associated with improved outcomes in cytogenetically normal acute myeloid leukemia (CN-AML). Interestingly, miR-181a expression was increased in CN-AML patients harboring CEBPA mutations, which are usually biallelic and associate with better...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-MTAB-1320 | biostudies-arrayexpress
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