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GenomicsCLK:BMAL1 is a pioneer-like transcription factor [CLK_ChIP]
The mammalian circadian clock relies on the master genes CLOCK (CLK) and BMAL1 and drives rhythmic gene expression to regulate biological functions under circadian control. We recently uncovered a surprising disconnect between the rhythmic binding of CLK:BMAL1 on DNA and the transcription of its tar...
ORGANISM(S): Mus musculus 
2014-01-06 | E-GEOD-47144 | biostudies-arrayexpress
GenomicsCLK:BMAL1 is a pioneer-like transcription factor [H2AZ-ChIP]
The mammalian circadian clock relies on the master genes CLOCK (CLK) and BMAL1 and drives rhythmic gene expression to regulate biological functions under circadian control. We recently uncovered a surprising disconnect between the rhythmic binding of CLK:BMAL1 on DNA and the transcription of its tar...
ORGANISM(S): Mus musculus 
2014-01-06 | E-GEOD-47143 | biostudies-arrayexpress
GenomicsCLK:BMAL1 is a pioneer-like transcription factor [MNase-Seq]
The mammalian circadian clock relies on the master genes CLOCK (CLK) and BMAL1 and drives rhythmic gene expression to regulate biological functions under circadian control. We recently uncovered a surprising disconnect between the rhythmic binding of CLK:BMAL1 on DNA and the transcription of its tar...
ORGANISM(S): Mus musculus 
2014-01-06 | E-GEOD-47142 | biostudies-arrayexpress
TranscriptomicsThe Oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs [miRNA-seq].
Using high throughput sequencing of Drosophila head RNA, a small set of miRNAs that undergo robust circadian oscillations in levels were discovered. We concentrated on a cluster of six miRNAs, mir-959-964, all of which peak at about ZT12 or lights-off. The data indicate that the cluster pri-miRNA is...
ORGANISM(S): Drosophila melanogaster 
2012-11-02 | E-GEOD-40943 | biostudies-arrayexpress
TranscriptomicsThe Oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs [expression].
Using high throughput sequencing of Drosophila head RNA, a small set of miRNAs that undergo robust circadian oscillations in levels were discovered. We concentrated on a cluster of six miRNAs, mir-959-964, all of which peak at about ZT12 or lights-off. The data indicate that the cluster pri-miRNA is...
ORGANISM(S): Drosophila melanogaster 
2012-11-02 | E-GEOD-40894 | biostudies-arrayexpress
TranscriptomicsThe Oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs.
This SuperSeries is composed of the following subset Series: GSE40894: The Oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs [expression]. GSE40943: The Oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs [miRNA-se...
ORGANISM(S): Drosophila melanogaster 
2012-11-02 | E-GEOD-40981 | biostudies-arrayexpress
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