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TranscriptomicsNascent elongating transcript sequencing (NET-seq) for Escherichia coli and Bacillus subtilis reveals a consensus pause sequence enriched at translation start sites.
Transcription by RNA polymerase (RNAP) is interrupted by pauses that play diverse regulatory roles. Although individual pauses have been studied in vitro, the determinants of pauses in vivo and their distribution throughout the bacterial genome remain unknown. Using nascent transcript sequencing we ...
ORGANISM(S): Bacillus subtilis 
2014-05-05 | E-GEOD-56720 | biostudies-arrayexpress
UnknownDelirium in Survivors of Cardiac Arrest Treated With Mild Therapeutic Hypothermia.
Not available
S-EPMC5240926 | biostudies-literature
ModelsKremers2015 - Thrombin Inhibitor Kinetics
Mathematical model of thrombin inhibition by ATIII, alpha-2-macroglobulin and miscellaneous serpins (a1-antitrypsin, a1-proteinase inhibitor, a1-antichymotrypsin, protease nexin-1, C1inhibitor and others).
2018-08-21 | MODEL1808210001 | BioModels
MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
TranscriptomicsTranscription profiling of proximal and distal muscle groups in dysferlin-deficient mice (C57BL/10.SJL_Dysf) to understand selective pattern of muscle involvement in muscular dystrophies
By comparing the transcriptome from proximal (quadriceps femoris, QF) and distal (tibialis anterior, TA)muscle groups in dysferlin deficient mouse muscle (the SJL mutation bred onto C57BL/10 to produces C57BL/10.SJL_Dysf) with proximal and distal muscle groups from control C57BL/10 mice of an equiva...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2629 | biostudies-arrayexpress
ProteomicsMultiplexed, scheduled high resolution sMRM-HR acquisition on full scan MS/MS instruments
Advances in software and high resolution, high mass accuracy mass spectrometers have expanded their functionality beyond traditional data dependent acquisition (DDA) methods. Using a single platform, an orthogonal quadrupole time-of flight (QqTOF) mass spectrometer, the TripleTOF 5600, we have inve...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Escherichia Coli (ncbitaxon:562) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-03-10 | MSV000079077 | MassIVE
UnknownEffect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial.
Not available
S-EPMC12055926 | biostudies-literature
GenomicsCohort-Based Genome-Wide Association Study of Glioma (GliomaScan)

We conducted a new independent GWAS of adult glioma using 1,856 cases and 4,955 controls from 14 cohort studies belonging to the Cohort Consortium, 3 case-control studies, and 1 population-based case only study. Cases were newly diagnosed glioma [ICDO-3 codes 9380-9480 or equivalent], and control...

phs000652.v1.p1 | EGA
MetabolomicsGNPS - MITOMICS: defining mitochondrial protein functions through deep multi-omic profiling
Mitochondria are epicenters of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of these organelles and have linked their dysfunction to over 150 distinct disorders. However, hundreds of mitochondrial proteins still lack clea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-11 | MSV000086685 | GNPS
UnknownA multi-center retrospective cohort study defines the spectrum of kidney pathology in Coronavirus 2019 Disease (COVID-19).
Not available
S-EPMC8328528 | biostudies-literature
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